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tag office of research integrity neuroscience microbiology

Magnifying glass over a DNA sequence
A Science Sleuth Accuses a Harvard Medical School Neuroscientist of Research Misconduct
Danielle Gerhard, PhD | Feb 15, 2024 | 5 min read
Researchers await the outcome of an ongoing investigation into dozens of instances of alleged image problems spanning 29 publications over a period of 23 years.
Haydeh Payami is wearing a purple dress and an orange and pink scarf and standing in front of a whiteboard.
A Microbial Link to Parkinson’s Disease
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 6 min read
Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Artist’s rendition of bright blue microbes among intestinal lining
Study Links Depression with High Levels of an Amino Acid
Dan Robitzski | Jun 14, 2022 | 5 min read
Experiments in animals and observations in humans suggest that the amount of proline circulating in one’s plasma has a strong association with depression severity.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
A white lab mouse peers over the wall of a sprawling maze
Bacterial Metabolite May Regulate Cognition in Mice
Sophie Fessl, PhD | Jun 3, 2022 | 3 min read
Microbes in the gut influence the death of support cells in the brain by producing isoamylamine, a study suggests.
Profile view of a newborn piglet being held by a veterinarian dressed in green.
Federal Investigators Probe Possible Misconduct in Pig Research
Dan Robitzski | Aug 30, 2022 | 2 min read
A quintet of research papers, all involving subjecting newborn piglets to brain damage, have been retracted because the data can’t be substantiated.
illustration of neurons in blue with synapses lighting up
Gut Molecule Linked to Decreased Myelination in Mouse Brains
Angie Voyles Askham, Spectrum | Feb 17, 2022 | 4 min read
A study shows that a molecule produced by intestinal microbes can enter the brain and that its presence is also associated with altered brain connectivity.
Nerve cell labelled with different colours
Psychedelics Slip Past Cell Membranes When Treating Depression
Alejandra Manjarrez, PhD | Feb 24, 2023 | 4 min read
The antidepressant properties of hallucinogenic drugs may stem from their ability to bind to intracellular serotonin receptors, a study suggests.

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