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SP140, an epigenetic reader protein mutated in a number of autoimmune disorders, is essential for macrophage function and preventing intestinal inflammation, scientists show. 

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image: Sex Differences in Immune Response

Sex Differences in Immune Response

By | June 21, 2016

Female mice lacking an immune receptor are better than males at fighting certain viral infections.

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image: Contributors

Contributors

By | June 1, 2016

Meet some of the people featured in the June 2016 issue of The Scientist.

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image: Toward Targeted Therapies for Autoimmune Disorders

Toward Targeted Therapies for Autoimmune Disorders

By | June 1, 2016

Training the immune system to cease fire on native tissues could improve outcomes for autoimmune patients, but clinical progress has been slow.

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image: Infection-Autism Link Explained?

Infection-Autism Link Explained?

By | January 31, 2016

A mouse study suggests a mechanism by which severe infections during pregnancy increase autism risk. 

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image: B Cells Can Drive Inflammation in MS

B Cells Can Drive Inflammation in MS

By | October 21, 2015

Researchers identify a subset of proinflammatory cytokine-producing B cells that may spark multiple sclerosis-related inflammation.  

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image: Body, Heal Thyself

Body, Heal Thyself

By | September 1, 2015

Reviving a decades-old hypothesis of autoimmunity

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image: Biotech Buys Autoimmune Firm for $7B

Biotech Buys Autoimmune Firm for $7B

By | July 16, 2015

Celgene has purchased Receptos, developer of an experimental multiple sclerosis drug.

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image: On the Flu Vax–Narcolepsy Link

On the Flu Vax–Narcolepsy Link

By | July 1, 2015

Researchers identify a peptide present in the swine-flu vaccine linked to narcolepsy that may be responsible for the sleep disorder.

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image: A Cancer Culprit in Autoimmunity

A Cancer Culprit in Autoimmunity

By | December 5, 2013

Scientists discover that cancer can drive the autoimmune disorder scleroderma.

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