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Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
The Genetics of Society
Claire Asher and Seirian Sumner | Jan 1, 2015 | 10 min read
Researchers aim to unravel the molecular mechanisms by which a single genotype gives rise to diverse castes in eusocial organisms.
The Scientist Staff | Mar 19, 2024
Arabidopsis Genome
Barry Palevitz | Jan 7, 2001 | 8 min read
Courtesy National Science Foundation Headlines on the morning of December 14, 2000, trumpeted the end of a presidential election that promised to go on forever. But if California Institute of Technology molecular biologist Elliot Meyerowitz had his way, the front page would have read differently: "Plant Genome Sequenced" at the top, then, lower down, "Election Decided - See Page 2." In a tour de force that capped a year of genome blockbusters, European, Japanese, and American scientists complet
New DNA/RNA Probe Applications Help To Unlock Secrets Of Genetics
James Kling | Nov 10, 1996 | 8 min read
SIDEBAR: Selected Suppliers of DNA and RNA Probes In the doctor's office or the research lab, the supreme value of DNA and RNA as diagnostic tools and the high potential of genetic therapy are putting a premium on DNA and RNA probes. Probes are short, single-stranded chains of nucleic acid that seek out and latch themselves to a complementary sequence of nucleic acids, often buried anonymously in a much larger section of DNA/RNA. Guanine on one chain links to a cytosine counterpart (G-C), and
Pufferfish Genomes Probe Human Genes
Ricki Lewis | Mar 17, 2002 | 7 min read
It may be humbling to think that humans have much in common with pufferfish, but at the genome level, the two are practically kissing cousins. "In terms of gene complement, we are at least 90% similar—probably higher. There are big differences in gene expression levels and alternate transcripts, but if you're talking about diversity, number and types of proteins, then it's pretty difficult to tell us apart," says Greg Elgar, group leader of the Fugu genome project at the Medical Research C
Genetic Testing's Political Implications Must Be Addressed
Dan Burk | Jul 20, 1997 | 6 min read
The recent public apology by President Clinton on behalf of the United States government to survivors of the Tuskegee syphilis experiments was intended to close the door on one of the most scandalous instances of officially sanctioned scientific misconduct in the annals of biomedical research. Yet, while the apology may bring closure to the particular incident, it stands as a stark reminder of the history that has led many minorities to distrust supposedly objective scientific research. Betraye
Short Shrift to Evolution?
Barry Palevitz and Ricki Lewis | Feb 1, 1999 | 7 min read
Editor's Note: In this essay, the authors--both scientists and writers--discuss recent news stories on evolution and express their opinions on how the stories were handled by the mainstream press. Evolution took center stage at the National Association of Biology Teachers (NABT) annual meeting in Reno, Nev., Nov. 3-8, 1998. If the teachers needed a theme, evolution was a logical choice--after all, it underlies and unifies contemporary biology. But NABT had other fish to fry. Despite a spate of c
When Stop Means Go
Ruth Williams | May 22, 2014 | 3 min read
A survey of trillions of base pairs of microbial DNA reveals a considerable degree of stop codon reassignment.
The Biggest Stories in Bioscience 2005
Ishani Ganguli | Dec 4, 2005 | 8 min read
Life scientists have been challenged more than ever this year not just to critically analyze data, but to better interpret those data for an increasingly critical public.

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