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image: NCI Gets Personal

NCI Gets Personal

By | June 2, 2015

The National Cancer Institute is launching a Phase 2 trial matching patients with specific mutations to drugs tailored to those genetic changes.

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Clinical Matchmaker

By | June 1, 2015

Enrolling the right patient population could be key to a successful clinical trial.

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image: Resistance Fighter

Resistance Fighter

By | June 1, 2015

Stuart Levy has spent a lifetime studying mechanisms of antibiotic resistance and crusading to abolish the use of antibiotics in animal feed.

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image: Viral Immunotherapy for Melanoma

Viral Immunotherapy for Melanoma

By | May 28, 2015

Phase 3 data from a clinical trial show a positive response to a melanoma treatment based on a modified herpesvirus.

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image: Cancer-Driving Mutations Common in Normal Skin Cells

Cancer-Driving Mutations Common in Normal Skin Cells

By | May 21, 2015

A deep-sequencing analysis reveals that non-malignant skin cells harbor many more cancer-driving mutations than previously expected. 

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image: Clinical Epidemiology Pioneer Dies

Clinical Epidemiology Pioneer Dies

By | May 18, 2015

Evidence-based medicine advocate David Sackett has passed away at age 80.

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Researchers develop a CRISPR-based, two-phage system that sensitizes resistant bacteria to antibiotics and selectively kills any remaining drug-resistant bugs. 

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Diagnosing Sepsis

By | May 14, 2015

An 11-gene set may help identify sepsis early, before it’s too late.

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image: Targeting Protein Domains with CRISPR

Targeting Protein Domains with CRISPR

By | May 13, 2015

Researchers use the genome-editing tool to mutate binding pockets and identify potential anti-cancer drug targets.

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image: Dino Snouts from Chicken Beaks

Dino Snouts from Chicken Beaks

By | May 13, 2015

Researchers tweak gene expression in chicken embryos that may have been crucial to the evolutionary transition from dinosaur noses to bird bills.

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