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An analysis of human cancer genome projects uncovers a counterintuitive loss of ribosomal gene copies.

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image: T Cells That Drive Toxic Shock in Mice Identified

T Cells That Drive Toxic Shock in Mice Identified

By | June 20, 2017

Overzealous activity by mucosa-associated invariant T (MAIT) cells in response to bacterial toxins can lead to illness instead of stopping it.

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A study suggests that “chief” cells in the stomach act as reserve stem cells that are activated by tissue damage and may be the long-sought source of gastric cancer.

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Research shows that human immunity develops much earlier than previously thought, but functions differently in adults.

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image: Trump Picks National Cancer Institute Director

Trump Picks National Cancer Institute Director

By | June 12, 2017

Ned Sharpless currently leads the cancer center at the University of North Carolina, Chapel Hill.

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image: Gene Mutations Foretell Immunotherapy Response

Gene Mutations Foretell Immunotherapy Response

By | June 12, 2017

A drug that blocks an immune checkpoint protein effectively treats tumors in patients with deficient DNA repair genes. 

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The new fossils push the origin of the human species back by 100,000 years.

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image: Mammals May Have a 12-Hour Clock

Mammals May Have a 12-Hour Clock

By | June 6, 2017

Data point to peaks in gene expression in the morning and evening that are distinct from day-night circadian cycles.

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The publicly available database found nearly a third of samples included mutations targeted by either approved drugs or therapies in clinical trials. 

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image: Contributors

Contributors

By | June 1, 2017

Meet some of the people featured in the June 2017 issue of The Scientist.

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