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image: CRISPR Corrects RNA-based Disease Defects

CRISPR Corrects RNA-based Disease Defects

By | August 10, 2017

In human cells, researchers deploy the genome editor to snip out toxic repetitive sequences.

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image: A Database of Genetic Differences Among Lab Mice

A Database of Genetic Differences Among Lab Mice

By | August 7, 2017

Researchers have catalogued mutations in the coding regions of 36 of the most important mouse strains.

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image: The Cancer Genes Needed for Immunotherapy Response

The Cancer Genes Needed for Immunotherapy Response

By | August 7, 2017

Using a large CRISPR-based screen, researchers find possible genetic culprits for patients not having success with immune checkpoint inhibitors.  

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image: The Ever-Expanding T-Cell World: A Primer

The Ever-Expanding T-Cell World: A Primer

By | August 7, 2017

Researchers continue to identify new T-cell subtypes—and devise ways to use them to fight cancer. The Scientist attempts to catalog them all.

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image: Fascinated by Folding

Fascinated by Folding

By | August 4, 2017

Lila Gierasch uses biochemical tools to understand how linear chains of amino acids turn into complex three-dimensional structures.

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image: Final Nail Hammered into NgAgo Coffin

Final Nail Hammered into NgAgo Coffin

By | August 3, 2017

The paper describing the gene-editing method is retracted.

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image: Details Published on CRISPR-treated Embryos

Details Published on CRISPR-treated Embryos

By | August 2, 2017

Scientists correct a mutation in fertilized eggs that causes a severe cardiac disease.

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image: Scientists Destroy Entire Chromosome with CRISPR

Scientists Destroy Entire Chromosome with CRISPR

By | August 1, 2017

Multiple DNA breaks at either the centromere or the long arm of the mouse Y chromosome cause it to fragment and disappear.

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image: Peer-Review Fraud Scheme Uncovered in China

Peer-Review Fraud Scheme Uncovered in China

By | July 31, 2017

The Chinese government finds almost 500 researchers guilty of misconduct in relation to a recent spate of retractions from a cancer journal.

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image: Human Genetic Variation May Complicate CRISPR

Human Genetic Variation May Complicate CRISPR

By | July 31, 2017

Slight sequence differences confound target sites in precision genome-editing, a study shows.

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