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tag cancer cell lines genetics genomics disease medicine
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD
| Mar 7, 2024
| 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening.
All Roads Lead to Genome Editing
Danielle Gerhard, PhD
| Feb 9, 2024
| 6 min read
Shondra Pruett-Miller has taken many paths in her career with her love of genome editing always as a guiding light.
Unlocking the Secrets within Cells Using Next Generation Sequencing
The Scientist
| Sep 25, 2023
| 1 min read
Next generation sequencing (NGS) core facility scientists and researchers discuss their latest work exploring novel cancer models and stem cells in space.
Silencing Epigenetic Complexes Re-sensitizes Drug-Resistant Cancer Cells
Rachael Moeller Gorman
| Sep 25, 2023
| 4 min read
Researchers studying lung cancer cell lines found that chromatin remodeling underlies one type of osimertinib resistance.
Precision Medicine: A New Era in Cancer Therapy
Rebecca Roberts, PhD
| Dec 15, 2023
| 6 min read
Precision medicine helps clinicians tailor individual treatments, addressing genetic mutations, tumor microenvironment variations, and therapeutic resistance.
Jumping Genes Put a Target on Cancerous Cells
Natalia Mesa, PhD
| Feb 14, 2023
| 4 min read
Two studies find that tumor-specific antigens are often peptides that result from a splicing event between exons and transposable elements.
Stem Cell Editing Repairs Severe Immunodeficiency
Kamal Nahas, PhD
| Mar 20, 2024
| 5 min read
Scientists hoping to treat immunodeficiencies using gene therapy have found a way to edit stem cells in mice without disrupting gene regulation.
Toppling the Genetic Dominoes in Bone Metastasis
Laura Tran, PhD
| Feb 15, 2024
| 4 min read
A key gene that fuels the molecular cascade driving prostate cancer bone metastasis progression may open avenues for targeted therapies.
Translation of “Jumping Genes” Creates Cancer Therapy Targets
Natalia Mesa, PhD
| Mar 29, 2023
| 4 min read
Researchers find many tumor-specific antigens form when cancer genes and transposable elements link up.
Tasmanian Devils Face Threats from Rapidly Evolving Facial Cancers
Natalia Mesa, PhD
| Jun 30, 2023
| 3 min read
A genetic study tracked the evolution of two transmissible cancers currently ravaging populations of Tasmanian devils.
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