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image: Nuclear Pores Come into Sharper Focus

Nuclear Pores Come into Sharper Focus

By and | December 1, 2016

Solving a long-standing structural puzzle will open the door to understanding one of the cell’s most enigmatic machines.

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Researchers use the CRISPR/Cas system to express three transcription-factor genes, changing the identities of mouse cells.

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image: Exercise Boosts Telomere Transcription

Exercise Boosts Telomere Transcription

By | July 27, 2016

Endurance exercise and metabolism are linked to transcriptional activation of human telomeres, researchers propose.

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image: Another Role for ApoE?

Another Role for ApoE?

By | January 20, 2016

Key Alzheimer’s disease–related protein may be a transcriptional regulator.

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image: Fearless about Folding

Fearless about Folding

By | January 1, 2016

Susan Lindquist has never shied away from letting her curiosity guide her research career.

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image: Shingo Kajimura: Fishing for Answers

Shingo Kajimura: Fishing for Answers

By | November 1, 2015

Assistant Professor, Department of Cell and Tissue Biology, University of California, San Francisco. Age: 39

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image: CRISPR–Enabled Epigenome Editing

CRISPR–Enabled Epigenome Editing

By | April 6, 2015

Researchers apply the genome-editing technology to alter histones at distant gene enhancers, controlling gene expression.

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image: Enhanced Enhancers

Enhanced Enhancers

By | November 1, 2014

The recent discovery of super-enhancers may offer new drug targets for a range of diseases.

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image: Next Generation: Freeze-Dried Gene Networks

Next Generation: Freeze-Dried Gene Networks

By | October 23, 2014

Researchers devise a way to preserve bits of paper containing synthetic gene networks, which can be easily stored and widely distributed. Rehydrated, transcription and translation “come to life.”

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image: Female Pigs May Sense Sex of Sperm

Female Pigs May Sense Sex of Sperm

By | May 21, 2014

The oviducts of pigs exhibit different gene expression profiles depending on their exposure to sperm with either an X or a Y chromosome, a study shows. 

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