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tag european medicines agency evolution developmental biology

Adaptive Evolution
Alla Katsnelson | Aug 1, 2009 | 7 min read
By Alla Katsnelson Adaptive Evolution A once-rare type of clinical trial that violates one of the sacred tenets of trial design is taking off, but is it worth the risk? Doriano Solinas When researchers at Pfizer first began a Phase 2 trial of an acute stroke therapy in 2000, they decided to take a novel approach. The study—called the ASTIN trial—would determine the drug’s optimal dose not with three or four diffe
Lasker Awards Target Developmental, Diagnostic Genetics
Rebecca Andrews | Sep 29, 1991 | 6 min read
The Laskers are among the most prestigious medical research awards in the world and among the oldest in the United States. Since they were first presented in 1944, 49 winners have gone on to win Nobel Prizes. Jordan Gutterman of the M.D. Anderson Cancer Center in Houston, executive vice president of the Albert and Mary Lasker Foundation, and director of the awards program since earlier this year, attributes the prestige of the awards to their longevity and to the "extraordinary quality&quo
An illustration of green bacteria floating above neutral-colored intestinal villi
The Inside Guide: The Gut Microbiome’s Role in Host Evolution
Catherine Offord | Jul 1, 2021 | 10+ min read
Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.
5 images related to stories highlighted in the article, including DNA strand, insect, and dog
Our Favorite Genetics Stories of 2021
Christie Wilcox, PhD | Dec 23, 2021 | 4 min read
Studies The Scientist covered this year illustrate the expanding importance of genetic and genomic research in all aspects of life science, from ecology to medicine.
Illustration showing a puzzle piece of DNA being removed
Large Scientific Collaborations Aim to Complete Human Genome
Brianna Chrisman and Jordan Eizenga | Sep 1, 2022 | 10+ min read
Thirty years out from the start of the Human Genome Project, researchers have finally finished sequencing the full 3 billion bases of a person’s genetic code. But even a complete reference genome has its shortcomings.
An illustration of flowers in the shape of the female reproductive tract
Uterus Transplants Hit the Clinic
Jef Akst | Aug 1, 2021 | 10+ min read
With human research trials resulting in dozens of successful deliveries in the US and abroad, doctors move toward offering the surgery clinically, while working to learn all they can about uterine and transplant biology from the still-rare procedure.
Week in Review: June 16–20
Tracy Vence | Jun 20, 2014 | 2 min read
Early Neanderthal evolution; developing antivirals to combat polio; the mouth and skin microbiomes; insect-inspired, flight-stabilizing sensors
Week in Review: March 27–31
Tracy Vence | Mar 31, 2017 | 3 min read
European Patent Office greenlights CRISPR patent; scientists reconsider a cancer drug target; NIH accepts preprints in grant applications; MERS drug developers test antibodies; experts weigh the risks and benefits of whole-exome sequencing for healthy people
Genetics-Based Testing Could Create A Biologic Underclass
Dorothy Nelkin | Nov 26, 1989 | 9 min read
[Editor’s note: Sophisticated biological tests that can uncover latent problems or predict future diseases have been developed over the past few years. Such tests have important clinical applications, but they also have found their way into nonclinical contexts in which they provide unprecedented threats to our traditional concepts of privacy and personal autonomy. So say Dorothy Nelkin and Laurence Tancredi, coauthors of a new book, Dangerous Diagnostics: The Social Power of Biological I
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.

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