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Transmission electron microscope image of Zika virus particles
T Cell–Boosting Zika Vaccine Protects Mice from the Virus
By avoiding the production of antibodies, something vaccines ordinarily induce, the immunization sidesteps the problem of antibody-dependent enhancement, which can amplify infection by a similar virus and is known to occur with dengue and Zika.
T Cell–Boosting Zika Vaccine Protects Mice from the Virus
T Cell–Boosting Zika Vaccine Protects Mice from the Virus

By avoiding the production of antibodies, something vaccines ordinarily induce, the immunization sidesteps the problem of antibody-dependent enhancement, which can amplify infection by a similar virus and is known to occur with dengue and Zika.

By avoiding the production of antibodies, something vaccines ordinarily induce, the immunization sidesteps the problem of antibody-dependent enhancement, which can amplify infection by a similar virus and is known to occur with dengue and Zika.

dengue, immunology

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A study of Nicaraguan children links prior Zika virus infection with aggravated dengue fever symptoms.
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Through groundbreaking studies on dengue and efforts to build scientific infrastructure in Latin America, the University of California, Berkeley, professor has bridged research with its benefits to society.
ade antibody-dependent enhancement ADE sars-cov-2 coronavorus pandemic covid-19 vaccine
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There is no evidence that any of the coronavirus vaccines in development worsen a coronavirus infection rather than confer immunity to it, but the phenomenon is something scientists are closely monitoring.
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Animal and cell culture studies show evidence that dengue antibodies can both neutralize and enhance Zika, but human investigations have only found protective effects.
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The drugs’ disruption of the microbiome makes a subsequent flavivirus infection more severe.
Dengue Infection Impairs Immune Defense Against Zika
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A memory B cell response to Zika virus in dengue-infected patients produced antibodies that were poorly neutralizing in vitro and instead enhanced infection.
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Researchers examine the blood of people infected with dengue virus, finding a few Zika-neutralizing antibodies among mostly enhancing ones.
Dengue’s Downfall?
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Researchers characterize a protein that could be key to the virus’s virulence—and to developing a vaccine against the mosquito-borne disease.
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