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image: First Data from Anti-Aging Gene Therapy

First Data from Anti-Aging Gene Therapy

By | April 25, 2016

A biotech company reports that an experimental treatment elongated its CEO’s telomeres. 

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image: Telomerase Overdrive

Telomerase Overdrive

By | January 1, 2016

Two mutations in a gene involved in telomere extension reverse the gene’s epigenetic silencing.

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image: Another Telomere-Regulating Enzyme Found

Another Telomere-Regulating Enzyme Found

By | November 12, 2015

Researchers identify a novel protein that helps maintain the length of chromosome-capping telomeres. 

1 Comment

image: Control ALT, Delete Cancer

Control ALT, Delete Cancer

By , and | April 1, 2015

Treating cancer by shutting down the alternative lengthening of telomeres (ALT) pathway

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image: Of Cells and Limits

Of Cells and Limits

By | March 1, 2015

Leonard Hayflick has been unafraid to speak his mind, whether it is to upend a well-entrenched dogma or to challenge the federal government. At 86, he’s nowhere near retirement.

3 Comments

image: Circular Chromosomes Straightened

Circular Chromosomes Straightened

By | November 6, 2014

A newly described method linearizes circular chromosomes in yeast and caps them with telomeres to mimic natural chromosomes.

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image: Anti-aging Pill Challenged

Anti-aging Pill Challenged

By | July 31, 2012

Former biotech executive files lawsuit accusing the company of engaging in deceptive business practices.

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image: The Aging and Inflammation Link

The Aging and Inflammation Link

By | May 24, 2012

A protein that keeps the immune response in check leads a double life as an anti-aging factor.

4 Comments

image: Telomere Basics

Telomere Basics

By | May 1, 2012

Telomeres are repetitive, noncoding sequences that cap the ends of linear chromosomes. They consist of hexameric nucleotide sequences (TTAGGG in humans) repeated hundreds to thousands of times. 

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Contributors

May 1, 2012

Meet some of the people featured in the April 2012 issue of The Scientist.

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