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tag noncoding dna ecology genetics genomics disease medicine

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Two sets of identical twin children sitting
Identical Twins Carry Distinctive Epigenetic Marks: Study
Chloe Tenn | Sep 30, 2021 | 2 min read
Researchers found more than 800 sites in the genome where the twins bore the same chemical tags.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Conceptual image showing molecules making up a brain shape
The Noncoding Regulators of the Brain
Christie Wilcox, PhD | Sep 12, 2022 | 10+ min read
Noncoding RNAs are proving to be critical players in the evolution of brain anatomy and cognitive complexity.
5 images related to stories highlighted in the article, including DNA strand, insect, and dog
Our Favorite Genetics Stories of 2021
Christie Wilcox, PhD | Dec 23, 2021 | 4 min read
Studies The Scientist covered this year illustrate the expanding importance of genetic and genomic research in all aspects of life science, from ecology to medicine.
Haydeh Payami is wearing a purple dress and an orange and pink scarf and standing in front of a whiteboard.
A Microbial Link to Parkinson’s Disease
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 6 min read
Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.
Artistic rendition of droplet DNA amplification
Finally, Scientists Sequence Single Cells with Long-Read Technology
Holly Barker, PhD | Mar 8, 2023 | 4 min read
By combining two innovative approaches, researchers can now sequence the full spectrum of mutational differences between individual cells’ genomes.
Blue 3D illustration of X-shaped chromosomes
X Chromosome Silenced in Some Cancers in Males
Natalia Mesa, PhD | Nov 11, 2022 | 3 min read
A study finds that XIST, the gene that shuts down one X chromosome in people who have two, is linked to cancer in males. 
The dark matter of disease
Hannah Waters | Apr 24, 2011 | 5 min read
Scientists are beginning to unravel how non-coding DNA works across long distances of the genome to influence disease
ribbon model of phenylalanine hydroxylase enzyme
Noncoding RNA Improves Symptoms in Mice with Metabolic Disorder
Abby Olena, PhD | Aug 6, 2021 | 4 min read
A long noncoding RNA from humans appeared to help the enzyme phenylalanine hydroxylase work better in a mouse model of phenylketonuria, the disorder characterized by reduced activity of that enzyme.

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