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tag enzymes developmental biology neuroscience

Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Top 7 in developmental biology
Bob Grant | Oct 4, 2010 | 3 min read
Check out the hottest papers in developmental biology and related fields, as ranked by F1000
Enzyme Checks Neuronal Growth
Kerry Grens | Dec 17, 2013 | 3 min read
A microtubule-severing enzyme curbs the regeneration of damaged nerve cells.
early-life stress, histone, chromatin, epigenetics, epigenetic modification, methylation, DNA, protein, stress, adversity, mice, genetics, genomics
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
Asher Jones | Mar 18, 2021 | 5 min read
In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
A mutated cell with a spiky membrane
Mutations in Autism-Linked Gene Cause Membrane Mischief
Holly Barker, PhD, Spectrum | Jan 26, 2023 | 4 min read
Inactivating TAOK1 prompts tentacle-like protrusions to form all over a neuron’s surface, revealing the gene’s role in molding the membrane.
Collage of faces
Remembering Those We Lost in 2022
Lisa Winter | Dec 26, 2022 | 5 min read
A look at some noteworthy scientists who died this year, leaving behind a legacy of research excellence.
Enzyme governs nerve polarity
Maria Anderson(manderson@the-scientist.com) | Jan 17, 2005 | 3 min read
Teams in China and Japan show how glycogen synthase kinase 3 regulates axon, dendrite growth
illustration of a branching neuron
Different Forms of Autism Have Opposite Problems with Brain Precursor Cells
Charles Choi | Jun 13, 2022 | 3 min read
Compared with cells taken from non-autistic controls, neural precursors from autistic boys proliferated in atypical ways, a small study finds.
illustration of neurons in blue with synapses lighting up
Gut Molecule Linked to Decreased Myelination in Mouse Brains
Angie Voyles Askham, Spectrum | Feb 17, 2022 | 4 min read
A study shows that a molecule produced by intestinal microbes can enter the brain and that its presence is also associated with altered brain connectivity.

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