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tag telomere cell molecular biology developmental biology

Telomere Biology
The Scientist Staff | Apr 12, 1998 | 3 min read
CELLULAR CLOCK: From left, University of Texas Southwestern Medical Center at Dallas investigators Michel Ouellette, Woodring Wright, Jerry Shay, and Shawn Holt continue to investigate how telomerase regulates human cell division. S.E. Holt, W.E. Wright, J.W. Shay, "Regulation of telomerase activity in immortal cell lines," Molecular and Cellular Biology, 16:2932-9, 1996. (Cited in more than 70 publications to date) Comments by Jerry W. Shay and Woodring E. Wright, department of cell biolog
Developmental Biology
The Scientist Staff | Jan 3, 1999 | 3 min read
L.B. Zimmerman, J.M. De Jesús-Escobar, R.M. Harland, "The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4," Cell, 86:599-606, 1996. (Cited in more than 180 papers since publication) Comments by Richard M. Harland, Choh Hao Li professor of biochemistry and molecular biology, University of California, Berkeley Richard M. Harland Researchers had long suspected that the protein noggin's interaction with bone morphogenetic proteins (BMPs) dictated devel
Microfluidics: Biology’s Liquid Revolution
Laura Tran, PhD | Feb 26, 2024 | 8 min read
Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.
Developmental Biology
The Scientist Staff | Nov 13, 1994 | 2 min read
K.G. Peters, D. Ornitz, S. Werner, L. Williams, "Unique expression pattern of the FGF receptor 3 gene during mouse organogenesis," Developmental Biology, 155:423-30, 1993. Kevin G. Peters (Department of Medicine, Division of Cardiology, Duke University Medical Center, Durham, N.C.): "Members of the fibroblast growth factor (FGF) family are powerful regulators of cell growth and differentiation that stimulate cells by activating spe
Developmental Biology
The Scientist Staff | Nov 13, 1994 | 2 min read
K.G. Peters, D. Ornitz, S. Werner, L. Williams, "Unique expression pattern of the FGF receptor 3 gene during mouse organogenesis," Developmental Biology, 155:423-30, 1993. Kevin G. Peters (Department of Medicine, Division of Cardiology, Duke University Medical Center, Durham, N.C.): "Members of the fibroblast growth factor (FGF) family are powerful regulators of cell growth and differentiation that stimulate cells by activating spe
Developmental Biology
The Scientist Staff | Jan 3, 1999 | 3 min read
S. Piccolo, Y. Sasai, B. Lu, E.M. De Robertis, "Dorsoventral patterning in Xenopus: Inhibition of ventral signals by direct binding of chordin to BMP-4," Cell, 86:589-98, 1996. (Cited in more than 170 papers since publication) Comments by Eddy M. De Robertis, Investigator, Department of Biological Chemistry, Howard Hughes Medical Institute, University of California, Los Angeles Eddy M. De Robertis In 1924, two scientists identified a small group of embryonic cells that tell their neighbor
Developmental Biology
The Scientist Staff | Apr 1, 1996 | 3 min read
Edited by Karen Young Kreeger H. Roelink, A. Augsburger, J. Heemskerk, V. Korzh, S. Norlin, A. Ruiz i Altaba, Y. Tanabe, M. Placzek, T. Edlund, T.M. Jessell, J. Dodd, "Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord," Cell, 76:761-75, 1994. (Cited in nearly 90 publications as of February 1996) Comments by Henk Roelink, University of Washington SIGNALS FROM SONIC HEDGEHOG: Using cDNA, University of Washington's Henk Roelink and col
Telomere Biology
The Scientist Staff | Jan 19, 1997 | 2 min read
Edited by: Karen Young Kreeger C.M. Counter, J. Gupta, C.B. Harley, B. Leber, S. Bacchetti, "Telomerase activity in normal leukocytes and hematologic malignancies," Blood, 85:2315-20, 1995. (Cited in nearly 50 publications as of December 1996) Comments by Silvia Bacchetti, McMaster University, Hamilton, Ontario, Canada. TALLYING TELOMERASE: McMaster University’s Silvia Bacchetti and Chris Counter were the first to detect telomerase in noncancerous somatic cells. The study of telomeres
Telomere Biology
Karen Young Kreeger | May 26, 1996 | 3 min read
N.W. Kim, M.A. Piatyszek, K.R. Prowse, C.B. Harley, M.D. West, P.L.C. Ho, G.M. Coviello, W.E. Wright, S.L. Weinrich, J.W. Shay, "Specific association of human telomerase activity with immortal cells and cancer," Science, 266:2011-5, 1994. (Cited in nearly 80 publications through April 1996) Comments by Jerry Shay, University of Texas Southwestern Medical Center, Dallas END RUN: Texas' Jerry Shay, left and Woody Wright developed a telomerase activity assay. Although telomeres-the tips of chro
Developmental Biology
The Scientist Staff | Feb 1, 1999 | 6 min read
Edited by: Paul Smaglik P. Carmeliet, V. Ferreira, G. Breier, S. Pollefeyt, L. Kieckens, M. Gertsenstein, M. Fahrig, A. Vandenhoeck, K. Harpal, C. Eberhardt, C. Declercq, J. Pawling, L. Moons, D. Collen, W. Risau, A. Nagy, "Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele," Nature, 380:435-9, 1996. (Cited in more than 235 papers since publication) Comments by Andras Nagy, senior staff scientist, Mount Sinai Hospital, Samuel Lunenfeld Research Institute, To

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