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tag single nucleotide polymorphism developmental biology evolution culture

GWAS, psychotic disorder, mood disorder, Q&A, bipolar disorder, schizophrenia, depression, sex differences
Genetic Variants Tied to Sex Differences in Psychiatric Disorders
Amanda Heidt | Mar 31, 2021 | 5 min read
The largest study of its kind identifies single nucleotide polymorphisms with disparate effects on men’s and women’s susceptibility to conditions such as bipolar disorder and schizophrenia.
Lasker Awards Target Developmental, Diagnostic Genetics
Rebecca Andrews | Sep 29, 1991 | 6 min read
The Laskers are among the most prestigious medical research awards in the world and among the oldest in the United States. Since they were first presented in 1944, 49 winners have gone on to win Nobel Prizes. Jordan Gutterman of the M.D. Anderson Cancer Center in Houston, executive vice president of the Albert and Mary Lasker Foundation, and director of the awards program since earlier this year, attributes the prestige of the awards to their longevity and to the "extraordinary quality&quo
Conceptual image showing molecules making up a brain shape
The Noncoding Regulators of the Brain
Christie Wilcox, PhD | Sep 12, 2022 | 10+ min read
Noncoding RNAs are proving to be critical players in the evolution of brain anatomy and cognitive complexity.
Can Viruses in the Genome Cause Disease?
Katarina Zimmer | Jan 1, 2019 | 10+ min read
Clinical trials that target human endogenous retroviruses to treat multiple sclerosis, ALS, and other ailments are underway, but many questions remain about how these sequences may disrupt our biology.
NIH Jumps Into Genetic Variation Research
Douglas Steinberg | Jan 18, 1998 | 9 min read
The field is given a boost by a widening of focus at the institutes as well as a report praising a major initiative. During the brief earthly tenure of the species Homo sapiens, the human genome seems to have accumulated just the right amount of variation to suit the purposes of geneticists. Single-nucleotide polymorphisms (SNPs), the DNA bases that vary systematically between subpopulations, are common enough to serve usefully as chromosomal markers but not so common as to make genetic analys
A Personal View of Genomics
Ricki Lewis | Nov 25, 2001 | 6 min read
It wasn't easy getting to the 4th International Meeting on Single Nucleotide Polymorphisms and Complex Genome Analysis held Oct. 10-15 at the Wenner-Gren Foundation in Stockholm. A week earlier, as flight cancellations continued in the wake of the Sept. 11 terrorist attacks, SwissAir had declared bankruptcy and an SAS jet had crashed in Milan, further disrupting schedules. So it was little surprise that several speakers had to phone in their talks. But not J. Craig Venter, president and chief sc
A California Chinook Salmon Jumps into a waterfall during spawning season
Geneticists Light Up Debate on Salmon Conservation
Christie Wilcox, PhD | Feb 1, 2023 | 10+ min read
Splitting Chinook salmon into two groups based on their DNA could aid conservation efforts. But some researchers argue that this would be a misuse of the data.
Illustration showing a puzzle piece of DNA being removed
Large Scientific Collaborations Aim to Complete Human Genome
Brianna Chrisman and Jordan Eizenga | Sep 1, 2022 | 10+ min read
Thirty years out from the start of the Human Genome Project, researchers have finally finished sequencing the full 3 billion bases of a person’s genetic code. But even a complete reference genome has its shortcomings.
Jason Holliday: Tree Tracker
Jef Akst | Feb 1, 2016 | 3 min read
Associate Professor, Virginia Tech, Department of Forest Resources and Environmental Conservation. Age: 37
Surpassing the Law of Averages
Jeffrey M. Perkel | Sep 1, 2009 | 7 min read
By Jeffrey M. Perkel Surpassing the Law of Averages How to expose the behaviors of genes, RNA, proteins, and metabolites in single cells. By necessity or convenience, almost everything we know about biochemistry and molecular biology derives from bulk behavior: From gene regulation to Michaelis-Menten kinetics, we understand biology in terms of what the “average” cell in a population does. But, as Jonathan Weissman of the University of Califo

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