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tag salt marshes evolution cell molecular biology

Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Cellular DNA and epigenetics
Do Epigenetic Changes Influence Evolution?
Katarina Zimmer | Nov 1, 2022 | 10+ min read
Evidence is mounting that epigenetic marks on DNA can influence future generations in a variety of ways. But how such phenomena might affect large-scale evolutionary processes is hotly debated.
The Sound of Salt
Sabrina Richards | Jan 30, 2013 | 3 min read
A putative ion channel integral to mammalian hearing turns out to be an elusive salt-sensing chemoreceptor in nematode worms.
Tag, You're It
Carina Storrs | Feb 1, 2014 | 7 min read
A guide to DNA-encoded libraries for drug discovery
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Illustration of blue and gray amino acids loosely forming protein
Fungal Cold Adaptation Linked to Protein Structure Changes: Study
Patience Asanga | Sep 20, 2022 | 4 min read
Environmental pressure seems to spawn changes in the intrinsically disordered regions of enzymes in polar yeasts, allowing them to adapt to extreme cold.
Tag! Purifying Proteins with Affinity Chromatography
Aileen Constans(aconstans@the-scientist.com) | Feb 27, 2005 | 6 min read
What is now a standard protein laboratory technique began as an act of desperation.
Gene evolution reversed
Chandra Shekhar | Aug 7, 2006 | 3 min read
Primordial vertebrate gene reconstructed by fusing its descendants
Using Transgenesis to Create Salt-Tolerant Plants
Ricki Lewis | Mar 3, 2002 | 6 min read
Crop agriculture has succeeded because growers have identified and cultivated useful plant variants through selective breeding and environmental alterations. Transgenic technology improves the precision of agriculture, modifying crops in ways that are uniquely useful that probably would not have arisen naturally. Salt tolerance is one such coveted trait. Recent research on promoting salt tolerance through transgenesis focuses on boosting salt-sequestering physiological mechanisms within species,

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