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tag receptor culture

A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Neurons (green) fire differently depending on whether the astrocytes (red) they are grown with are cultivated from people with or without fragile X.
Astrocytes Fuel Erratic Firing in Fragile X Neurons
Lauren Schenkman, Spectrum | May 30, 2023 | 4 min read
This new understanding could one day lead to targeted treatments. 
A mutated cell with a spiky membrane
Mutations in Autism-Linked Gene Cause Membrane Mischief
Holly Barker, PhD, Spectrum | Jan 26, 2023 | 4 min read
Inactivating TAOK1 prompts tentacle-like protrusions to form all over a neuron’s surface, revealing the gene’s role in molding the membrane.
Transport Breakdown
Kate Yandell | Jul 1, 2013 | 2 min read
Deficiencies in a cellular motor that carries a serotonin receptor are associated with anxiety in mice.
The Chemistry of Attraction
Michelle Vettese-dadey | Mar 5, 2000 | 6 min read
Chemokines and their receptors help direct cell migration to sites of inflammation. You heard it here--chemokine receptors and ligands are in. Inflammation, cancer, asthma, rheumatoid arthritis, angiogenesis, and AIDS are just a few areas in which chemokines and their receptors are crucial. Therefore, chemokine pathways represent potentially valuable therapeutic targets. Asthma, one of the most common chronic diseases in the industrialized world, is recognized as an inflammatory disease, and ste
Making Things Grow: Insect Cells, Stem Cells, and Primary Cell Lines All Pose Challenges for Cell Culturists
Laura Defrancesco | Jun 21, 1998 | 5 min read
Date: June 22, 1998 Insect Cell Culture Media, Suppliers of Primary Cell Culture Media Advantages for Protein Expression Studies Since the mid-1950s cultures of insects--cockroaches, fruit flies, and leafhoppers, to name a few--have been the object of quiet study by physiologists and cell biologists. But along came genetic engineering and suddenly insect cultures have been put in the spotlight since they provide advantages over both bacterial and mammalian systems for recombinant protein prod
Cancer's Other Conduit
The Scientist Staff | Sep 7, 2003 | 7 min read
Courtesy of Elsevier  DEADLY SPREAD: A: an insulinoma (Ins) in a Rip1Tag2 transgenic mouse. LYVE-1 immunohistochemistry demonstrates the presence of lymphatic vessels in connective tissue, but not near islets of Langerhans. B: Rip1Tag2 mice were crossed with mice which overexpress VEGF-C in pancreatic b-cells. C: An insulinoma cell breaks through a lymphatic vessel. D: An intralymphatic tumor cell mass forms. E: In a lymph node, lymphocytes (L) are surrounded by tumor cells (T). F: Immunof
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
The Scientist Staff | Mar 19, 2024
A scanning electron micrograph of a coculture of E. coli and Acinetobacter baylyi. Nanotubes can be seen extending from the E. coli.
What’s the Deal with Bacterial Nanotubes?
Sruthi S. Balakrishnan | Jun 1, 2021 | 10+ min read
Several labs have reported the formation of bacterial nanotubes under different, often contrasting conditions. What are these structures and why are they so hard to reproduce?

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