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image: Chemogenetics Doesn’t Work Like Many Thought

Chemogenetics Doesn’t Work Like Many Thought

By | August 4, 2017

A study finds the so-called DREADD method of manipulating neurons using a drug called CNO actually works via clozapine.

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image: Endocannabinoids in the Groove

Endocannabinoids in the Groove

By | July 17, 2017

The system responsible for the buzz humans get from marijuana plays a passel of physiological roles outside the brain.

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The cell-surface receptor, SIRP-alpha, initiates the innate immune response in hosts.  

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Research shows that human immunity develops much earlier than previously thought, but functions differently in adults.

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The 19th century biologist’s drawings, tainted by scandal, helped bolster, then later dismiss, his biogenetic law.

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Time-lapse imaging shows the immune cells transferring chemical signals during pigment pattern formation in developing zebrafish.

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image: Infographic: How the Zebrafish Got Its Stripes

Infographic: How the Zebrafish Got Its Stripes

By | May 1, 2017

Immune cells called macrophages shuttle cellular messages in the skin.

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The lungs of extremely premature lambs supported in a closed, sterile environment that enables fluid-based gas exchange grow and develop normally, researchers report.

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image: Image of the Day: Stop Signals

Image of the Day: Stop Signals

By | April 17, 2017

Transcytosis, suppression of vesicle traffic across cells, helps reduce permeability in the blood-retinal barrier during development.

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image: Image of the Day: Tubular Origins

Image of the Day: Tubular Origins

By | March 23, 2017

Murine neural tubes, with each image highlighting a different embryonic tissue type (blue). The neural tube itself (left) grows into the brain, spine, and nerves, while the mesoderm (middle) develops into other organs, and the ectoderm (right) forms skin, teeth, and hair.

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