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Engineered T cells (blue) become activated when they're near the glioblastoma in a mouse brain, leading to the cancer cells being killed.
Environmental Cues Keep CAR T Cells on Track
Pairing CARs with a synthetic receptor makes T cells more lethal tumor killers.
Environmental Cues Keep CAR T Cells on Track
Environmental Cues Keep CAR T Cells on Track

Pairing CARs with a synthetic receptor makes T cells more lethal tumor killers.

Pairing CARs with a synthetic receptor makes T cells more lethal tumor killers.

cell therapy, neuroscience

Fresh asparagus sliced horizontally, revealing inner microchannel structure.
Food for Thought: A Recipe for Regenerating Nerves
Iris Kulbatski, PhD | Oct 23, 2023 | 3 min read
Al dente asparagus stalks may hold the key to successful neural stem cell therapy for repairing injured axons.
Conceptual dot-based image of an eye on a predominantly blue background.
On-Again, Off-Again Connections Advance Eye Regeneration
Iris Kulbatski, PhD | Jul 10, 2023 | 3 min read
Researchers track neural connections between retinal cells in a dish to understand their therapeutic potential.
CAR T Cells Derived from Stem Cells Target HIV Tissue Reservoirs in Monkeys
Berly McCoy, PhD | May 25, 2021 | 3 min read
Transplanted CAR stem cells persisted long term and showed multilineage engraftment in tissues that harbor HIV.
Engineered Immune Cells Eliminate Brain Cancer in Mice
Brooke Dulka, PhD | May 25, 2021 | 2 min read
Researchers developed a new CAR T-cell therapy that targets specific growth factor receptors in glioblastoma to eliminate brain tumors.
CRISPR Technologies for the New Era of Cell and Gene Therapy
The Scientist | Nov 25, 2020 | 1 min read
Experts will discuss how they use new CRISPR technologies to advance their cell and gene therapy research.
Pelizaeus-Merzbacher disease neural stem cell transplantation
Neural Stem Cell Transplantation Crawls Toward the Clinic
Ashley P. Taylor | Oct 29, 2019 | 9 min read
Several early-stage clinical trials indicate that implanting patients with the cells is safe. But whether they can alleviate neurological problems remains to be seen.
Parkinson’s Patient Transplanted with Neurons Derived from iPSCs
Ashley P. Taylor | Nov 14, 2018 | 2 min read
This is the first time researchers have tested the use of the reprogrammed stem cells in the human brain.
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