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bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Genomic Methylation Collector
Beth Marie Mole | Oct 21, 2012 | 2 min read
A parasitic worm accumulates epigenetic DNA tags over its lifetime.  
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
When Stop Means Go
Ruth Williams | May 22, 2014 | 3 min read
A survey of trillions of base pairs of microbial DNA reveals a considerable degree of stop codon reassignment.
An illustration of green bacteria floating above neutral-colored intestinal villi
The Inside Guide: The Gut Microbiome’s Role in Host Evolution
Catherine Offord | Jul 1, 2021 | 10+ min read
Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.
A scanning electron micrograph of a coculture of E. coli and Acinetobacter baylyi. Nanotubes can be seen extending from the E. coli.
What’s the Deal with Bacterial Nanotubes?
Sruthi S. Balakrishnan | Jun 1, 2021 | 10+ min read
Several labs have reported the formation of bacterial nanotubes under different, often contrasting conditions. What are these structures and why are they so hard to reproduce?
Those We Lost in 2019
Ashley Yeager | Dec 30, 2019 | 6 min read
The scientific community said goodbye to Sydney Brenner, Paul Greengard, Patricia Bath, and a number of other leading researchers this year.
A Pioneer Presses Search For 'Other Side of Biology'
Gerald Edelman | Nov 13, 1988 | 4 min read
When I was a high school student, I came across Erwin Schrödingers What Is Life?. I still remember my exultant reaction—a combination of adolescent pride in feeling able to understand ideas considered beyond a young person’s means, and a genuine intellectual thrill engendered by the problems that Schrödinger addressed. Upon rereading the book, it appears to me that its major value was to provoke interest in a central problem of biology. Schrödinger’s question
Contributors
Diana Kwon | May 1, 2017 | 4 min read
Meet some of the people featured in the May 2017 issue of The Scientist.
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.

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