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The Scientist

» structural biology

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image: Crystal Unclear

Crystal Unclear

By | October 15, 2015

A behind-the-scenes look at how researchers solved the high-resolution crystal structure of the nucleosome core particle raises the age-old question of assigning credit in science.

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image: Characterizing DNA Quadruplexes

Characterizing DNA Quadruplexes

By | September 10, 2015

Researchers are developing new techniques to better understand how and why knots of DNA are distributed throughout the genome.

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image: Neutralizing HIV

Neutralizing HIV

By | June 18, 2015

Engineered immunogens based on conserved patches of the virus’s envelope protein point to new strategies for vaccine design.

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image: Spider and Centipede Venom Remarkably Similar

Spider and Centipede Venom Remarkably Similar

By | June 12, 2015

The predatory toxins employed by animals separated by millions of years of evolution are virtually identical, a study shows.

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image: RNA Stucturomics

RNA Stucturomics

By | June 1, 2015

A new high-throughput, transcriptome-wide assay determines RNA structures in vivo.

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image: Renowned Molecular Biologist Dies

Renowned Molecular Biologist Dies

By | May 6, 2015

Alexander Rich, discoverer of Z-DNA, the RNA-DNA double helix, and the structure of collagen, has passed away at age 90.

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image: Crystal Structure, Murky Function

Crystal Structure, Murky Function

By | January 29, 2015

Scientists have determined the crystal structures of bacterial translocator proteins, but their functions remain unclear.

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image: Mitochondrial Enzyme Detailed

Mitochondrial Enzyme Detailed

By | January 9, 2015

Researchers reveal clues regarding how an ancient mitochondrial enzyme helps maintain healthy cells across the tree of life.

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image: DNA Bends Control Gene Activation

DNA Bends Control Gene Activation

By | March 25, 2014

Genomic structures called i-motifs signal DNA activation, while hairpin loops signal gene suppression.  

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image: Intracellular Spirals

Intracellular Spirals

By | December 1, 2013

Membrane twists connect stacked endoplasmic reticulum sheets.

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