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image: Deep Pocket Exploration

Deep Pocket Exploration

By | February 1, 2017

A modification to traditional docking software enables the examination of a ligand’s passage into its receptor.

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image: Infographic: Modeling Molecules’ Receptor Binding

Infographic: Modeling Molecules’ Receptor Binding

By | February 1, 2017

A software upgrade follows ligands step-wise into their binding sites on receptors.

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image: Unknown Protein Structures Predicted

Unknown Protein Structures Predicted

By | January 19, 2017

Metagenomic sequence data boosts the power of protein modeling software to yield hundreds of new protein structure predictions.

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image: Video: Inner Circle

Video: Inner Circle

By | December 1, 2016

See an animation that illustrates emerging insights into the inner ring structures of the nuclear pore complex.

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The ribosome-associated organelle consists of tightly packed tubes, not flat sheets as previously believed, according to new super-resolution microscopy images.

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image: Week in Review: September 5–9

Week in Review: September 5–9

By | September 9, 2016

Environmental magnetite in the human brain; prion structure takes shape; watching E. coli evolve in real time; learning from others’ behavior 

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image: First Glimpse at Infectious Prion Shape

First Glimpse at Infectious Prion Shape

By | September 8, 2016

The preliminary structure of the misfolded protein that causes mad cow disease and Creutzfeldt-Jakob disease looks like a coiled mattress spring.

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image: Zooming In on an Antidepressant Target

Zooming In on an Antidepressant Target

By | April 6, 2016

Structural studies reveal how SSRI drugs bind to the human serotonin transporter.

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image: Crystal Unclear

Crystal Unclear

By | October 15, 2015

A behind-the-scenes look at how researchers solved the high-resolution crystal structure of the nucleosome core particle raises the age-old question of assigning credit in science.

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image: Characterizing DNA Quadruplexes

Characterizing DNA Quadruplexes

By | September 10, 2015

Researchers are developing new techniques to better understand how and why knots of DNA are distributed throughout the genome.

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