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Developmental Biology
The Scientist Staff | Apr 1, 1996 | 3 min read
Edited by Karen Young Kreeger H. Roelink, A. Augsburger, J. Heemskerk, V. Korzh, S. Norlin, A. Ruiz i Altaba, Y. Tanabe, M. Placzek, T. Edlund, T.M. Jessell, J. Dodd, "Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord," Cell, 76:761-75, 1994. (Cited in nearly 90 publications as of February 1996) Comments by Henk Roelink, University of Washington SIGNALS FROM SONIC HEDGEHOG: Using cDNA, University of Washington's Henk Roelink and col
DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Microfluidics: Biology’s Liquid Revolution
Laura Tran, PhD | Feb 26, 2024 | 8 min read
Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.
Molecular Biology
The Scientist Staff | Feb 17, 1991 | 3 min read
R.J. Bandziulis, M.S. Swanson, G. Dreyfuss, "RNA-binding proteins as developmental regulators," Genes and Development, 3, 431-7, April 1989. Gideon Dreyfuss (University of Pennsylvania School of Medicine, Philadelphia): "Protein structural comparisons led to the discovery of identifying and unifying features shared by RNA-binding proteins of the nucleus and cytoplasm. Many of these ribonucleoproteins contain an RNA-binding domain (RBD) of approximately 90 amino acids. This amino acid sequence
Molecular Biology
The Scientist Staff | Feb 3, 1991 | 3 min read
T. Hai, F. Liu, W.J. Coukos, M.R. Green, "Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers," Genes and Development, 3, 2083-90, December 1989. Michael R. Green (University of Massachusetts Medical Center, Worcester, Mass.): "I suspect that this paper may have attracted more than the usual attention because it is relevant to several research areas, and some of the results were unexpected. We and others had bee
The figure shows two waves made of DNA double helixes representing gene expression changes in the malaria parasite and its human host. These changes reveal a synchronization between parasite and host.
Malaria Parasites Sync with Hosts’ Molecular Rhythms
Mariella Bodemeier Loayza Careaga, PhD | Sep 1, 2023 | 2 min read
Evidence of malaria parasites aligning with their human hosts may pave the way for new antimalarial agents.
A person moving the hands of a vintage clock backwards.
Synthetic Circuits Reveal the Key to Rewinding the Cellular Clock
Charlene Lancaster, PhD | Mar 12, 2024 | 4 min read
Using a circuit-based system, scientists determined the ideal transcription factor levels to promote the successful reprogramming of fibroblasts into induced pluripotent stem cells.
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
mixing blue and pink smoke, symbolic of the muddled boundaries between sexes
Opinion: Biological Science Rejects the Sex Binary, and That’s Good for Humanity
Agustín Fuentes | May 12, 2022 | 5 min read
Evidence from various sciences reveals that there are diverse ways of being male, female, or both. An anthropologist argues that embracing these truths will help humans flourish.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.

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