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Redesigning Medicine Using Synthetic Biology
Alison Halliday, PhD, Technology Networks | Jun 21, 2023 | 5 min read
Drawing inspiration from nature, synthetic biology offers exciting opportunities to transform the future of medicine.
DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Telomere Biology
The Scientist Staff | Apr 12, 1998 | 3 min read
CELLULAR CLOCK: From left, University of Texas Southwestern Medical Center at Dallas investigators Michel Ouellette, Woodring Wright, Jerry Shay, and Shawn Holt continue to investigate how telomerase regulates human cell division. S.E. Holt, W.E. Wright, J.W. Shay, "Regulation of telomerase activity in immortal cell lines," Molecular and Cellular Biology, 16:2932-9, 1996. (Cited in more than 70 publications to date) Comments by Jerry W. Shay and Woodring E. Wright, department of cell biolog
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Tiled blue-gray MRI readouts of a human brain.
Cancer Tied to Reduced Risk of Alzheimer’s Disease
Dan Robitzski | Apr 14, 2022 | 7 min read
Observational evidence for the connection is solidifying, and some clues are emerging about the mechanisms that may explain it.
Journal club logo on purple background
The Scientist's Journal Club: Transcriptomics
The Scientist | Sep 20, 2023 | 2 min read
Scientists discuss their latest findings on immune cell dynamics, neurodegenerative disease risk factors, and rare cell types obtained from bulk and single cell RNA sequencing experiments.
Genetic Neurologist: A Profile of Huda Zoghbi
Anna Azvolinsky | Nov 1, 2018 | 8 min read
Turning to molecular genetics, the Baylor pediatric neurologist and geneticist works to discover the biological basis for the rare neurological diseases she sees in her patients.
Exploring the Past, Present, and Future of Brain Organoids 
Niki Spahich, PhD | Feb 18, 2024 | 5 min read
Paola Arlotta seeks to understand the complex symphony of brain development in vitro by using organoid models.
Molecular Multitasking
Carina Storrs | Aug 1, 2013 | 6 min read
Commercial kits use fluorescent beads to probe dozens of cytokines in one reaction.
Top 7 in cell biology
Cristina Luiggi | Sep 20, 2010 | 2 min read
1. Parasite's unusual metabolism __Plasmodium falciparum__ may have evolved a unique, non-cyclic version of the textbook energy-producing process in cells known as the Krebs cycle -- presumably as an adaptation to living inside human blood cells -- a finding that could lead to new Malaria drug targets. K.L. Olszewski et al., linkurl:Nature,;http://www.ncbi.nlm.nih.gov/sites/entrez/20686576?dopt=Abstract&holding=f1000,f1000m,isrctn 2010 Aug 2 466:774-8. linkurl:Eval by;http://f1000biology.com/a

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