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A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
SYNGAP1 helps neurons eliminate old synapses and form new ones after a novel experience (left and center left)—a process weakened in mice missing a copy of the gene (center right and right).
Autism-Linked Gene SYNGAP1 Molds Synaptic Plasticity, Learning
Angie Voyles Askham, Spectrum | Oct 26, 2021 | 4 min read
The finding may help to explain why people with SYNGAP1 mutations tend to have learning difficulties and a high tolerance for pain.
Scientists Engineer Dreams to Understand the Sleeping Brain
Catherine Offord | Dec 1, 2020 | 10+ min read
Technologies such as noninvasive brain stimulation and virtual reality gaming offer insights into how dreams arise and what functions they might serve.
Immune System Maintains Brain Health
Amanda B. Keener | Nov 1, 2016 | 10+ min read
Once thought only to attack neurons, immune cells turn out to be vital for central nervous system function.
Underground Supermodels
Thomas J. Park and Rochelle Buffenstein | Jun 1, 2012 | 10+ min read
What can a twentysomething naked mole-rat tell us about fighting pain, cancer, and aging?
African Sleeping Sickness: A Recurring Epidemic
Ricki Lewis | May 12, 2002 | 5 min read
African trypanosomiasis is making an unwelcome comeback. But unlike other returning diseases, this one has a drug treatment—eflornithine—that disappeared from the market when it failed to cure cancer. Yet like Viagra's origin from a curious side effect in a clinical trial, so too was eflornithine reborn. "When it was discovered that it removes mustaches in women, it suddenly had a market: western women with mustaches," says Morten Rostrup, president of the international council for M
Cell-Signaling A Cascade of Kinases, Phosphatases, and Cytokines
Deborah Noble | Jul 4, 1999 | 8 min read
Date: July 5, 1999Table of Cell Signaling Tools At today's research pace, new signaling mechanisms within and between cells are emerging not one by one but in a chain reaction. Each new discovery has strong implications for previously established models, sometimes overturning several assumptions at once. With such a large number of interacting systems--from cell adhesion to differentiation and apoptosis--and receptor pathways, keeping up with the wealth of cell-signaling research tools can be l

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