Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
A study finds that expression levels of certain genes that track with brain activity—particularly those involved in brain development—vary between people with autism and their non-autistic peers.
In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.
Chloe Williams, Spectrum | Aug 19, 2022 | 5 min read
Troves of sequencing data reveal genes tied to autism through different variant types, providing a more complete picture of the condition’s genetic roots and new clues to its heterogeneity.