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tag encode cell molecular biology developmental biology

Developmental Biology
The Scientist Staff | Jan 3, 1999 | 3 min read
L.B. Zimmerman, J.M. De Jesús-Escobar, R.M. Harland, "The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4," Cell, 86:599-606, 1996. (Cited in more than 180 papers since publication) Comments by Richard M. Harland, Choh Hao Li professor of biochemistry and molecular biology, University of California, Berkeley Richard M. Harland Researchers had long suspected that the protein noggin's interaction with bone morphogenetic proteins (BMPs) dictated devel
Microfluidics: Biology’s Liquid Revolution
Laura Tran, PhD | Feb 26, 2024 | 8 min read
Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.
Developmental Biology
The Scientist Staff | Nov 13, 1994 | 2 min read
K.G. Peters, D. Ornitz, S. Werner, L. Williams, "Unique expression pattern of the FGF receptor 3 gene during mouse organogenesis," Developmental Biology, 155:423-30, 1993. Kevin G. Peters (Department of Medicine, Division of Cardiology, Duke University Medical Center, Durham, N.C.): "Members of the fibroblast growth factor (FGF) family are powerful regulators of cell growth and differentiation that stimulate cells by activating spe
Developmental Biology
The Scientist Staff | Nov 13, 1994 | 2 min read
K.G. Peters, D. Ornitz, S. Werner, L. Williams, "Unique expression pattern of the FGF receptor 3 gene during mouse organogenesis," Developmental Biology, 155:423-30, 1993. Kevin G. Peters (Department of Medicine, Division of Cardiology, Duke University Medical Center, Durham, N.C.): "Members of the fibroblast growth factor (FGF) family are powerful regulators of cell growth and differentiation that stimulate cells by activating spe
Developmental Biology
The Scientist Staff | Jan 3, 1999 | 3 min read
S. Piccolo, Y. Sasai, B. Lu, E.M. De Robertis, "Dorsoventral patterning in Xenopus: Inhibition of ventral signals by direct binding of chordin to BMP-4," Cell, 86:589-98, 1996. (Cited in more than 170 papers since publication) Comments by Eddy M. De Robertis, Investigator, Department of Biological Chemistry, Howard Hughes Medical Institute, University of California, Los Angeles Eddy M. De Robertis In 1924, two scientists identified a small group of embryonic cells that tell their neighbor
Developmental Biology
The Scientist Staff | Apr 1, 1996 | 3 min read
Edited by Karen Young Kreeger H. Roelink, A. Augsburger, J. Heemskerk, V. Korzh, S. Norlin, A. Ruiz i Altaba, Y. Tanabe, M. Placzek, T. Edlund, T.M. Jessell, J. Dodd, "Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord," Cell, 76:761-75, 1994. (Cited in nearly 90 publications as of February 1996) Comments by Henk Roelink, University of Washington SIGNALS FROM SONIC HEDGEHOG: Using cDNA, University of Washington's Henk Roelink and col
Developmental Biology
The Scientist Staff | Feb 1, 1999 | 6 min read
Edited by: Paul Smaglik P. Carmeliet, V. Ferreira, G. Breier, S. Pollefeyt, L. Kieckens, M. Gertsenstein, M. Fahrig, A. Vandenhoeck, K. Harpal, C. Eberhardt, C. Declercq, J. Pawling, L. Moons, D. Collen, W. Risau, A. Nagy, "Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele," Nature, 380:435-9, 1996. (Cited in more than 235 papers since publication) Comments by Andras Nagy, senior staff scientist, Mount Sinai Hospital, Samuel Lunenfeld Research Institute, To
Molecular Biology
The Scientist Staff | Dec 9, 1990 | 1 min read
M. Horikoshi, C.K. Wang, H. Fujii, J.A. Cromlish, et al., "Cloning and structure of a yeast gene encoding a general transcription initiation factor TFIID that binds to the TATA box," Nature, 341, 299-303, 28 September 1989. Masami Horikoshi (Rockefeller University, New York): "This paper describes the cloning of the gene encoding the TATA box [a conserved sequence of bases]-binding factor TFIID [transcription factor IID], which we and others have shown to be a key factor in both basic promoter
Molecular Biology
The Scientist Staff | Dec 9, 1990 | 1 min read
S. Hahn, S. Buratowski, P.A. Sharp, L. Guarente, "Isolation of the gene encoding the yeast TATA binding protein TFIID: a gene identical to the SPT15 suppressor of Ty element insertions," Cell, 58, 1173-81, 22 September 1989. Steven Hahn (Fred Hutchinson Cancer Research Center, Seattle): "TFIID is one of the essential components in the machinery necessary to initiate transcription by RNA polymerase II. For eight years after the discovery of TFIID in mammals, little was known about it because of
Molecular Biology
The Scientist Staff | Nov 22, 1992 | 2 min read
L.-H. Tsai, E. Harlow, M. Meyerson, "Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase," Nature, 353:174-7, 1991. Li-Huei Tsai (Massachusetts General Hospital Cancer Center, Charlestown, Mass.): "Regulation of the onset of cellular DNA synthesis appears to be an important mechanism for small DNA tumor viruses to immortalize cells. Both the retinoblastoma gene product (pRB) and cyclin A, two of the adenovirus E1A targeted cellular proteins, hav

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