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tag encode evolution disease medicine ecology

bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
An illustration of green bacteria floating above neutral-colored intestinal villi
The Inside Guide: The Gut Microbiome’s Role in Host Evolution
Catherine Offord | Jul 1, 2021 | 10+ min read
Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.
Dating the Origin of Us
Ajit Varki | Nov 1, 2013 | 5 min read
Theoretical anthropogeny seeks to understand how Homo sapiens rose to a position of global dominance.
The Proteasome: A Powerful Target for Manipulating Protein Levels
John Hines and Craig M. Crews | May 1, 2017 | 10+ min read
The proteasome’s ability to target and degrade specific proteins is proving useful to researchers studying protein function or developing treatments for diseases.
Illuminating Behaviors
Douglas Steinberg | Jun 1, 2003 | 6 min read
Courtesy of Genevieve Anderson If not for Nobel laureates Thomas Hunt Morgan, Eric R. Kandel, and Sydney Brenner, the notion of a general behavioral model might seem odd. Behaviors, after all, are determined by an animal's evolutionary history and ecological niche. They are often idiosyncratic, shared in detail only by closely related species. But, thanks to Morgan's research in the early 20th century, and Kandel's and Brenner's work over the past 35 years, the fly Drosophila melanogaster, t
TIGR Introduces Vibrio cholerae Genome
Ricki Lewis | Aug 20, 2000 | 6 min read
The bacterium that causes cholera has joined the elite club of organisms whose genomes have been sequenced. Since 1817, seven pandemics of cholera have left millions dead from the dehydration caused by relentless diarrhea. But the disease has been noted for at least 1,000 years. "Cholera is one of the most ancient diseases we know about. Its home is the Ganges delta in India and Bangladesh; it has a long history there. It became a worldwide disease in 1817, when the first pandemic started
tazmanian devils fighting cancer
Some Cancers Become Contagious
Katarina Zimmer | Apr 1, 2019 | 10+ min read
So far, six animal species are known to carry transmissible, “parasitic” forms of cancer, but researchers are still mystified as to how cancer can become infectious.
Genetic Parasites and a Whole Lot More
Barry Palevitz | Oct 15, 2000 | 10+ min read
Photo: Ori Fragman, Hebrew University Hordeum spontaneum, the plant studied for BARE-1 retroelements. With genome sequences arriving almost as regularly as the morning paper, the public's attention is focused on genes--new genes to protect crops against pests; rogue genes that make bacteria resistant to antibiotics; faulty genes that, if fixed, could cure diseases such as muscular dystrophy. What many people don't realize is that genes account for only part of an organism's DNA, and in many c
Using Gene Drives to Limit the Spread of Malaria
Tony Nolan and Andrea Crisanti | Jan 1, 2017 | 10 min read
Introducing genetic changes into mosquito populations could be key to effective malaria control.
Going Viral
Breeann Kirby and Jeremy J. Barr | Sep 1, 2013 | 10+ min read
From therapeutics to gene transfer, bacteriophages offer a sustainable and powerful method of controlling microbes.

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