epigenetic, genetics & genomics

Obese mice that exercised while pregnant gave birth to pups that grew up free of the metabolic issues present in the adult young of sedentary obese mothers—possibly by staving off epigenetic changes to a key metabolic gene.

Researchers could accurately detect life-threatening vascular complications in type 2 diabetes patients by analyzing hydroxymethylated cytosines in freely circulating DNA.

The diurnal cycles of the microbiome alter the activity of a protein produced by the host, and in turn guide histone acetylation, gene expression, and metabolic activity.

The unborn chicks translate auditory alarms from adult birds into quaking vibrations.

Breast cancer researcher and oncologist Nancy Davidson discusses what we’ve learned from the first wave of epigenetic trials for breast cancer, and what challenges lie ahead before such therapies reach the clinic.

A study suggests that the direct transfer of DNA methylation marks from one generation to the next is much less common than scientists previously thought.

Male rodents exposed to nicotine had changes in sperm genome methylation and produced pups and grandpups with abnormal behavior.

Methylation patterns at so-called metastable epialleles in the genome stamp a memory into each of our cells.

A study of chemical tags on histone proteins hints at how the same genome can yield very different animals.

The use of targetable chromatin modifiers has ushered in a new era of functional epigenomics.