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tag france neuroscience cell molecular biology

A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
black-and-white brain scan showing tumor
Glioblastoma Cells Imitate Immature Neurons to Invade the Brain
Sophie Fessl, PhD | Aug 5, 2022 | 3 min read
Neuron-like glioblastoma cells are the pioneers of deadly tumors’ spread through the brain, contributing to their devastating invasiveness, a study in mice finds.
Can Single Cells Learn?
Catherine Offord | May 1, 2021 | 10+ min read
A controversial idea from the mid-20th century is attracting renewed attention from researchers developing theories for how cognition arises with or without a brain.
Complete model of fly brain neuron connections
How Larval Fruit Fly Brains Convert Sensory Signals to Movement
Laura Dattaro, Spectrum | Mar 10, 2023 | 4 min read
A wiring map diagrams more than half a million neuronal connections in the first complete connectome of Drosophila and holds clues about which brain architectures best support learning.
Top 7 in cell biology
Cristina Luiggi | Sep 20, 2010 | 2 min read
1. Parasite's unusual metabolism __Plasmodium falciparum__ may have evolved a unique, non-cyclic version of the textbook energy-producing process in cells known as the Krebs cycle -- presumably as an adaptation to living inside human blood cells -- a finding that could lead to new Malaria drug targets. K.L. Olszewski et al., linkurl:Nature,;http://www.ncbi.nlm.nih.gov/sites/entrez/20686576?dopt=Abstract&holding=f1000,f1000m,isrctn 2010 Aug 2 466:774-8. linkurl:Eval by;http://f1000biology.com/a
A mutated cell with a spiky membrane
Mutations in Autism-Linked Gene Cause Membrane Mischief
Holly Barker, PhD, Spectrum | Jan 26, 2023 | 4 min read
Inactivating TAOK1 prompts tentacle-like protrusions to form all over a neuron’s surface, revealing the gene’s role in molding the membrane.
Coronal section of a brain
Immunity-Linked Genes Expressed Differently in Brains of Autistic People
Laura Dattaro, Spectrum | Jan 11, 2023 | 4 min read
Data from postmortem brain tissues adds to the evidence that inflammation is associated with autism.
What Paraspeckles Can Teach Us About Basic Cell Biology
Archa Fox | Dec 1, 2019 | 10+ min read
Discovering a new type of subnuclear body taught me how pursuing the unexpected can lead to new insights—in this case, about long noncoding RNAs and liquid-liquid phase separation in cells.
Cancer cell
Interrogating the Complexities of the Tumor Microenvironment
Alison Halliday, PhD, Technology Networks | May 19, 2023 | 5 min read
Gaining a better understanding of the dynamic and reciprocal interactions between cancer cells and the tumor microenvironment is essential for improving patient diagnosis and treatment.

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