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tag melanoma immunology disease medicine culture

Imagining a Cure
Nicholas P. Restifo and Megan Bachinski | Apr 10, 2011 | 5 min read
For cancer patients, close is not good enough.
custom targeted cancer vaccine
Personalized Cancer Vaccines in Clinical Trials
Jasreet Hundal and Elaine R. Mardis | Jul 15, 2019 | 10+ min read
The field is young, but predicting antigens produced by patients’ malignant cells could yield successful treatments for individuals with a range of cancer types.
A New Place in Human Immunology
Cynthia Fox | Jun 11, 2000 | 9 min read
Four class 1 molecules are constructed around a fragment of protein from a virus to make a tetramer Which of the following comments are immunologists making about the tetramer assay these days? A) "It's changed our life." B) "It's just an assay." If you answered "both," you're up on your immunology. The tetramer is just an assay, but it's been making immunologists giddy in the last few years. Peter Doherty of St. Jude Children's Research Hospital made the first statement (wh
Illustration of clear cells with orange nuclei, Toxoplasma gondii, on colorful background
Turning Toxoplasma Against Cancer
Annie Melchor | Jan 3, 2022 | 9 min read
Several research groups have found that Toxoplasma gondii infection can ramp up antitumor immune responses in mice. Can the single-cell parasite be used to develop safe treatments for humans?
Guts and Glory
Anna Azvolinsky | Apr 1, 2016 | 9 min read
An open mind and collaborative spirit have taken Hans Clevers on a journey from medicine to developmental biology, gastroenterology, cancer, and stem cells.
Harnessing Stem Cell–Like T Cells to Better Fight Cancer
Daniel E. Speiser and Werner Held | Jul 13, 2020 | 9 min read
Better understanding the CD8+ T cells already present in tumors could be key to making immunotherapies work for more patients.
T Cells and Neurons Talk to Each Other
Ashley Yeager | Oct 1, 2020 | 10+ min read
Conversations between the immune and central nervous systems are proving to be essential for the healthy social behavior, learning, and memory.
lab tools cancer therapy
Contending with Resistance in Cancer Immunotherapy
Marissa Fessenden | Apr 1, 2019 | 7 min read
Researchers describe ways to study how cancer cells evade therapies that harness the immune system.
A nude (hairless) mouse, typically used in biomedical and drug discovery research methods that rely on immunodeficient mouse strains.
Brush Up: Humanized Mice: More than the Sum of Their Parts
Deanna MacNeil, PhD | Aug 31, 2022 | 5 min read
Scientists study human health in vivo with modified mice that molecularly mimic human biology.
Hot Papers
The Scientist Staff | May 13, 1990 | 1 min read
S.A. Rosenberg, B.S. Packard, P.M. Aebersold, D. Solomon, et al., "Use of tumor-infiltrating lymphocytes and interleukin-2 in the immunotherapy of patients with metastatic melanoma," New England Journal of Medicine, 319, 1676-80, 22 December 1988. Steve Rosenberg (National Cancer Institute, Bethesda, Md.): "The three standard treatments for patients with cancer are surgery, radiotherapy, and chemotherapy. These treatments can cure about one half of all individuals who develop the disease. Thos

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