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tag induced pluripotent stem cells neuroscience genetics genomics microbiology culture

Pluripotent Until Needed
Beth Marie Mole | Apr 1, 2013 | 7 min read
Microarrays help keep induced pluripotent stem cell lines in check, from start to finish.
On the left is a normally developing mouse embryo, on the right is a slightly larger mouse embryo that also contains horse cells that glow green.
Chimera research opens new doors to understanding and treating disease
Hannah Thomasy, PhD, Drug Discovery News | Aug 9, 2023 | 10 min read
Animals with human cells could provide donor organs or help us understand neuropsychiatric disorders.
Developing Brains in Dishes
Ashley P. Taylor | Apr 26, 2017 | 3 min read
Two studies report methods to mimic human fetal brain development using neurons derived from human induced pluripotent stem cells that form 3-D, brain-like structures. 
Artist’s rendition of a neuron silhouetted against a glowing red background.
SNO-y Protein Levels Help Explain Why More Women Develop Alzheimer’s
Dan Robitzski | Jan 6, 2023 | 4 min read
Female postmortem brains contain more S-nitrosylated C3 proteins, likely linked to menopause, which instruct immune cells to kill neuronal synapses.
Harnessing Stem Cells to Model Neurological Disorders
The Scientist | Apr 15, 2021 | 2 min read
Gene-Edited Organoids Explore Neanderthal Brain Function
Jef Akst | Feb 12, 2021 | 3 min read
Using CRISPR to swap an archaic variant of the NOVA1 gene into human stem cells, researchers create organoids with neurodevelopmental differences from those carrying modern DNA.
Making Things Grow: Insect Cells, Stem Cells, and Primary Cell Lines All Pose Challenges for Cell Culturists
Laura Defrancesco | Jun 21, 1998 | 5 min read
Date: June 22, 1998 Insect Cell Culture Media, Suppliers of Primary Cell Culture Media Advantages for Protein Expression Studies Since the mid-1950s cultures of insects--cockroaches, fruit flies, and leafhoppers, to name a few--have been the object of quiet study by physiologists and cell biologists. But along came genetic engineering and suddenly insect cultures have been put in the spotlight since they provide advantages over both bacterial and mammalian systems for recombinant protein prod
Genetic Diversity in the Brain
Ruth Williams | Oct 31, 2013 | 3 min read
Neurons within a person’s brain exhibit striking variations in DNA copy number.
Stem Cell Discoveries Stir Debate
Douglas Steinberg | Nov 12, 2000 | 9 min read
Editor's Note: This is the first of two articles on questions raised by recent stem cell discoveries. The second article, focusing on various organs and the nervous system, will appear in the Nov. 27 issue of The Scientist. Researchers first isolated embryonic stem cells (ESCs) from mouse blastocysts almost 20 years ago, and a paper announcing the discovery of human ESCs emerged in 1998. Adult-derived stem cells (ASCs) have since become the rage in certain quarters of biology, with unexpected--
Combating COVID-19 with Cell-Free Expression
The Scientist | Aug 19, 2020 | 6 min read
Scientists rely on synthetic biology and cell-free expression systems for developing novel approaches to combat the pandemic.

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