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tag extracellular matrix genetics genomics neuroscience

Bugs as Drugs to Boost Cancer Therapy
Danielle Gerhard, PhD | Jan 18, 2024 | 7 min read
Bioengineered bacteria sneak past solid tumor defenses to guide CAR T cells’ attacks.
The Psychiatrist’s Jigsaw
Megan Scudellari | Nov 1, 2013 | 10+ min read
Researchers are piecing together the devilishly complex sets of genetic alterations underlying schizophrenia and bipolar disorder.
Study Pinpoints Potential “Master Regulator” of Age-Related Cognitive Decline
Shawna Williams | Dec 18, 2017 | 4 min read
Upping a gene’s expression in rat brains made them better learners and normalized the activity of hundreds of other genes to resemble the brains of younger animals.
bacteria inside a biofilm
How Bacterial Communities Divvy up Duties
Holly Barker, PhD | Jun 1, 2023 | 10+ min read
Biofilms are home to millions of microbes, but disrupting their interactions could produce more effective antibiotics.
Cancer cell
Interrogating the Complexities of the Tumor Microenvironment
Alison Halliday, PhD, Technology Networks | May 19, 2023 | 5 min read
Gaining a better understanding of the dynamic and reciprocal interactions between cancer cells and the tumor microenvironment is essential for improving patient diagnosis and treatment.
Scanning electron micrograph (SEM) of the unicellular yeast Saccharomyces cerevisiae, known as Baker's or Brewer's yeast.
Yeast Models Provide New Insights into Neurodegenerative Diseases
Mahlon Collins | Oct 1, 2021 | 10+ min read
The single-celled fungus allows researchers to study Alzheimer’s, Parkinson’s, ALS and other brain diseases with unparalleled speed and scale.
Genome Economy
Ricki Lewis | Jun 10, 2001 | 10 min read
The Human Genome Project's discovery1 that the human body runs on an instruction manual of a mere 35,000 or so genes--compared to the worm's 19,000, the fruit fly's 13,000, and the tiny mustard relative Arabidopsis thaliana's 25,000--placed humanity on an even playing field with these other, supposedly simpler, organisms. It was a humbling experience, but humility quickly gave way to awe with the realization that the human genome might encode 100,000 to 200,000 proteins. Scientists base this num
The Genes of Parkinson’s Disease
Bobby Thomas and M. Flint Beal | Feb 1, 2011 | 10 min read
The minority of Parkinson’s cases now known to have genetic origins are shedding light on the cellular mechanisms of all the rest, bringing researchers closer to a cause—and perhaps a cure.
2017 Top 10 Innovations
The Scientist | Dec 1, 2017 | 10+ min read
From single-cell analysis to whole-genome sequencing, this year's best new products shine on many levels.
Research Notes
Brendan Maher | Aug 19, 2001 | 2 min read
Likening his discovery to a paleontologist unearthing a new dinosaur species, Vladimir Kapitonov, a staff scientist at the Genetic Information Research Institute, recently revealed a new class of transposable elements in eukaryotes. These jumping genes use rolling circle replication--an ancient process characteristic of some plasmid replication in bacteria--to copy and insert itself throughout entire genomes (V.V. Kapitonov, J. Jurka, "Rolling circle transposons in eukaryotes," Proceedings of th

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