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tag light sheet microscopy cell molecular biology disease medicine

Microscopic image of a live amoeba.
Illuminating Specimens Through Live Cell Imaging
Charlene Lancaster, PhD | Mar 14, 2024 | 8 min read
Live cell imaging is a powerful microscopy technique employed by scientists to monitor molecular processes and cellular behavior in real time.
Improvements In Light Microscopy Lead To New Applications
Holly Ahern | Nov 24, 1991 | 6 min read
Hosts of new applications have turned the light microscope into an exquisitely sensitive measuring device that can be used to image dynamic cellular events right down to the molecular level. Indeed, dramatic improvements in optical microscopy have brought about a renaissance in the use of light microscopes in biology and medicine. And within the last few years, the combination of novel optical systems with video and digital image processing capabilities have opened up whole new fields of resear
The mouse peripheral nervous system with nerve cells farther away from the camera represented in yellow and pink, while nerves closer to the camera are shown in blue tones.
A Glowing Mouse Map
Mariella Bodemeier Loayza Careaga, PhD | Feb 1, 2024 | 2 min read
A whole-body immunostaining method allowed researchers to achieve cellular resolution at the whole-organism level.
2022 Top 10 Innovations 
2022 Top 10 Innovations
The Scientist | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
Zebrafish with fluorescent nervous system in green.
Oust the Mouse: A Plan to Reduce Mammal Use in Drug Development
Natalia Mesa, PhD | Mar 15, 2022 | 7 min read
The Scientist spoke to Mount Desert Island Biological Laboratory’s Jim Strickland about the institute’s new MDI Bioscience initiative to perform more drug testing and development in nonmammalian models.
Image of the tissue surrounding a pancreatic tumor thickening and scarring.
How Pancreas Injuries Can Cause Cancer in Mice
Dan Robitzski | Nov 9, 2021 | 4 min read
A key mutation turns healing cells into cancer promoters.
Confocal Microscopy: Viewing Cells As """"Wild Animals""""
Franklin Hoke | Jan 24, 1993 | 6 min read
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Abstract graphene structures
Synthetic Organelles Let Researchers Control Cell Behavior
Catherine Offord | Nov 1, 2021 | 3 min read
A technique that reversibly bundles tagged cargo into artificial membraneless compartments gives scientists the ability to switch cell processes on and off.
Light Microscopy Enables Scientists to Peer Inside Cells In Real Time
Holly Ahern | Jan 21, 1996 | 9 min read
Although the laws of physics dictate how much an object can be magnified and still clearly seen, scientists continue to expand their view of the microscopic world beyond the cellular level. New light microscopy methods and technology have made it possible for scientists to view previously undetectable tiny structures inside of cells, and to examine such objects in real time as cells carry out their activities. "New microscopy techniques, particularly those involving fluorescence microscopy and
New Dimensions in Confocal Microscopy
Mike May | Jul 27, 2003 | 4 min read
New Dimensions in Confocal Microscopy PerkinElmer's new UltraVIEW RS microscope produces real-time images in six dimensions Courtesy of PerkinElmer A protein's function depends on its movement inside a cell and interactions with other proteins and biological structures. Biologists who want to watch proteins working in living cells frequently turn to confocal microscopy. "Confocal microscopy is critical for modern cell biology and physiology," says Michael Nathanson of the Yale University Sc

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