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tag quantitative pcr immunology culture ecology disease medicine

PCR Primed To Spur Chain Of Applications
Holly Ahern | Jun 25, 1995 | 10+ min read
What would you do if your research interests revolved around obtaining DNA from a bacterium preserved for millions of years in the gut of a bee stuck in amber, matching up a murderer to crime- scene blood half a century old, or cloning genes from a 1,000- year-old mummy? Most scientists would first consider PCR--the polymerase chain reaction--as a technique for approaching problems such as these. With PCR, minute quantities of nucleic acids can be amplified millions of times into sufficient qua
Top 10 Innovations 2013
The Scientist | Dec 1, 2013 | 10+ min read
The Scientist’s annual competition uncovered a bonanza of interesting technologies that made their way onto the market and into labs this year.
2020 Top 10 Innovations
The Scientist | Dec 1, 2020 | 10+ min read
From a rapid molecular test for COVID-19 to tools that can characterize the antibodies produced in the plasma of patients recovering from the disease, this year’s winners reflect the research community’s shared focus in a challenging year.
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
Lurking in the Shadows
Bob Grant | Dec 1, 2014 | 10+ min read
Bats harbor diverse pathogens, including Ebola, Marburg, SARS, and MERS viruses. Understanding why could help researchers stymie deadly emerging diseases.
Going Their Separate Ways: A Profile of Products for Cell Separation
Michelle Vettese-dadey | Sep 12, 1999 | 10+ min read
Date: September 13, 1999Cell Separation Products Magnetic Cell Separation Technologies that isolate rare cell types to high purity are essential to the cell biology researcher. Understanding cell developmental pathways becomes increasingly significant as diagnosis and treatment of disease turns more to the molecular level.1 This diagnosis of cell-related diseases requires methods for detection, isolation, and analysis of individual cells regardless of their frequency.2 The hematopoietic system
2009 Top 10 Innovations
The Scientist | Dec 1, 2009 | 10+ min read
#featureArticleHeadWrapper img { border:none; float:none; margin:5px 0; }#featureArticleContent p.comment { font-weight: bold; color: #333333; font-size: 11px; line-height: 15px; }span.judge_1 { color: #E93593; } span.judge_2 { color: #20BCED; } span.judge_3 { color: #C1CD2F; } span.judge_4 { color: #F69723; } The Scientist Top 10 Innovations: 2009 The ten most exciting tools to hit the life sciences this year. It’s b
Distinguishing Th1 and Th2 Cells
Jeffrey Perkel | May 13, 2001 | 10+ min read
Reagents That Distinguish Th1 and Th2 cells Courtesy of R&D SystemsSchematic representation of cytokines influencing the development of antigen-activated naive CD4+ T cells into Th1 and Th2 cells. Editor's note: Although individual techniques are associated with specific researchers in this article, it should be noted that these investigators commonly use several different techniques to analyze T lymphocyte populations. The human body is constantly under siege. It must defend itself fr
Research Notes
Ricki Lewis | Jun 11, 2000 | 5 min read
Microcolumns Collapse in Alzheimer's Brain Tangles and plaques are hallmarks of the Alzheimer's brain. Thanks to a technique borrowed from statistical physics, researchers from Boston University, the University of Minnesota, and Bar-Ilan University in Israel have quantified another sign: microcolumns of 11 neurons that are noticeably diminished in the Alzheimer's brain, and less so in the related condition Lewy body dementia. Using brains from a brain bank, the researchers probed a part of the
Porcine Possibilities
Ricki Lewis | Oct 15, 2000 | 8 min read
Courtesy of PPL TherapeuticsA new generation of pigs. Headlines in late summer 2000 introduced long-awaited reports on pig cloning and retroviral transmission to mice, pig cells healing rat spinal cords, and a gaff by Dolly dad Ian Wilmut erroneously heralding halt of xenograft work at the Roslin Institute near Edinburgh, Scotland. So it seemed that the question of whether pigs can pass their retroviruses to humans might finally be on the road to resolution. Not quite. Pigs, as the purveyors o

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