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tag music ecology culture developmental biology cell molecular biology

Microfluidics: Biology’s Liquid Revolution
Laura Tran, PhD | Feb 26, 2024 | 8 min read
Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Exploring the Past, Present, and Future of Brain Organoids 
Niki Spahich, PhD | Feb 18, 2024 | 5 min read
Paola Arlotta seeks to understand the complex symphony of brain development in vitro by using organoid models.
Monoclonal Antibodies Find Utility In Cell Biology
Ricki Lewis | Dec 11, 1994 | 10+ min read
But, just as antibodies are finding increasing utility in cell biology, a new Food and Drug Administration classification for those products with clinical utility may affect researchers' access to the important technology (see accompanying story). Monoclonal History MAbs were born in 1975, when Georges Kohler and Cesar Milstein at the Medical Research Council Laboratories in Cambridge, England, fused two types of cells to form a hy
Monoclonal Antibodies Find Utility In Cell Biology
Ricki Lewis | Dec 11, 1994 | 10+ min read
But, just as antibodies are finding increasing utility in cell biology, a new Food and Drug Administration classification for those products with clinical utility may affect researchers' access to the important technology (see accompanying story). Monoclonal History MAbs were born in 1975, when Georges Kohler and Cesar Milstein at the Medical Research Council Laboratories in Cambridge, England, fused two types of cells to form a hy
Stem cells for brain cancer
Peter B. Dirks | Apr 1, 2006 | 3 min read
FEATUREThe Ecology of Tumors Stem cells for brain cancer BY PETER B. DIRKSNeural stem cell biology took off in 1992 when Brent Reynolds and Samuel Weiss, working at the University of Calgary, discovered that culturing mammalian brain cells in serum-free conditions (in EGF and bFGF), yielded clonally derived colonies of undifferentiated neural cells (neurospheres). This culture system demonstrated that cells within these colonies showed cardinal pr
Guts and Glory
Anna Azvolinsky | Apr 1, 2016 | 9 min read
An open mind and collaborative spirit have taken Hans Clevers on a journey from medicine to developmental biology, gastroenterology, cancer, and stem cells.
The Cell’s Integrated Circuit: A Profile of Lucy Shapiro
Anna Azvolinsky | Aug 1, 2018 | 9 min read
Shapiro helped to found the field of systems biology.
Music, the Brain, and Williams Syndrome
Brendan Maher | Nov 25, 2001 | 9 min read
Gloria Lenhoff is a 46-year-old lyric soprano singer who has performed with such diverse groups as the San Diego Master Chorale and members of Aerosmith. She can sing nearly 2,500 songs in more than 25 languages, reportedly in a perfect accent. She even has perfect pitch. But the rest of her world is not perfect. Gloria is affected by a rare genetic disorder called Williams syndrome. With an IQ of about 55, Gloria literally cannot subtract three from five or make change for a dollar. But what
Surpassing the Law of Averages
Jeffrey M. Perkel | Sep 1, 2009 | 7 min read
By Jeffrey M. Perkel Surpassing the Law of Averages How to expose the behaviors of genes, RNA, proteins, and metabolites in single cells. By necessity or convenience, almost everything we know about biochemistry and molecular biology derives from bulk behavior: From gene regulation to Michaelis-Menten kinetics, we understand biology in terms of what the “average” cell in a population does. But, as Jonathan Weissman of the University of Califo

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