Jeffrey Perkel | Jun 20, 2004 | 10+ min read
MOLECULAR CARTOGRAPHY:Recognizing that much of the cell's work is done not by individual proteins but by large macromolecular complexes, researchers increasingly are trying to map protein-protein interactions throughout the cell. This map of the C. elegans interaction network, or "interactome," links 2,898 proteins (nodes) by 5,460 interactions (edges). (reprinted with permission, Science, 303:540–3, 2004.)If you want a sense of one of the hottest trends in biology today, open the hood of