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March TSS
Genomes Across the Tree of Life
Researchers turn to unique eukaryotes to better understand how DNA is organized in 3D space.
Genomes Across the Tree of Life
Genomes Across the Tree of Life

Researchers turn to unique eukaryotes to better understand how DNA is organized in 3D space.

Researchers turn to unique eukaryotes to better understand how DNA is organized in 3D space.

genome architecture

The giant virus <em >Pandoravirus neocaledonia&nbsp;</em>inside the amoeba <em>Acanthamoeba castellanii</em>.
Giant Viruses Grew Out of Small Ones: Study
Kamal Nahas, PhD | Feb 13, 2023 | 4 min read
A study employing CRISPR/Cas9 to explore the evolutionary beginnings of some giant viruses finds evidence their large genomes arose from gene duplications.
A view of the nucleus of a cell with DNA in blue, RNA in pink, and associated proteins in yellow and purple
DNA Methylation Influences Replication and Genome Organization
Abby Olena, PhD | Sep 22, 2021 | 3 min read
A study links the loss of DNA methylation across the genome—as is common in cancer—to the disruption of the 3-D compartments that organize the genome and to the timing of DNA replication.
A microscope image of a dinoflagellate.
Dinoflagellate Genome Structure Unlike Any Other Known
Amanda Heidt | May 10, 2021 | 5 min read
The transcription of DNA drives the remarkably tidy organization of chromosomes in the dinoflagellate Symbiodinium microadriaticum.
Researchers Fuse Chromosomes to Create New Yeast Strains
Diana Kwon | Aug 1, 2018 | 4 min read
Saccharomyces cerevisiae showed only minor alterations in growth and gene expression when its 16 chromosomes were combined.
DNA Loop-the-Loops
Kate Yandell | Dec 11, 2014 | 4 min read
A new full-genome map indicates how DNA is folded within the nuclei of human cells.
Architecture Reveals Genome’s Secrets
Sabrina Richards | Nov 25, 2012 | 4 min read
Three-dimensional genome maps are leading to a deeper understanding of how the genome’s form influences its function.
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