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tag glucose metabolism developmental biology disease medicine genetics genomics

bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Two babies engaged in conversation, with one shouting in the other’s ear
Nurturing Early Language Skills Prevents the Behavioral Expression of a Genetic Trait
Iris Kulbatski, PhD | Jul 11, 2022 | 4 min read
A new precision medicine approach is making life sweeter for infants unable to metabolize milk sugar.
High-Throughput Epigenetics Analyses
Jyoti Madhusoodanan | Jan 1, 2018 | 7 min read
Emerging technologies help researchers draw mechanistic links between metabolism and epigenetic modification of DNA.
Advances in the functional characterization of newly discovered microproteins hint at their diverse roles  in health and disease
The Dark Matter of the Human Proteome
Annie Rathore | Apr 1, 2019 | 10 min read
Advances in the functional characterization of newly discovered microproteins hint at diverse roles in health and disease.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Week in Review: May 23–27
Tracy Vence | May 27, 2016 | 2 min read
Potential link between microbial infection and Alzheimer’s disease; CRISPR-enabled cell lineage tracing; image irregularities lead to anticipated retraction; brain glucose metabolism and consciousness; exploring emotional contagion; Zika-related microcephaly risk estimated
The Biological Roots of Intelligence
Shawna Williams | Nov 1, 2018 | 10+ min read
Imaging, behavioral, and genetic data yield clues to what’s behind effective thinking.
Conceptual image showing molecules making up a brain shape
The Noncoding Regulators of the Brain
Christie Wilcox, PhD | Sep 12, 2022 | 10+ min read
Noncoding RNAs are proving to be critical players in the evolution of brain anatomy and cognitive complexity.
Whole-Genome SNP Genotyping
Marilee Ogren | Jun 1, 2003 | 8 min read
Clockwise from top left: images courtesy of Affymetrix, Illumina, Sequenom and Illumina Take any two individuals, sequence and compare their genomic DNA, and you'll find that the vast majority (about 99.9%) of the sequences are identical. In the remaining 0.1% lie differences in disease susceptibility, environmental response, and drug metabolism. Researchers are understandably keen to dissect these variations, most of which take the form of single-nucleotide polymorphisms (SNPs). A SNP (pron
Protein Synthesis Enzymes Have Evolved Additional Jobs
Amber Dance | Jun 1, 2020 | 10+ min read
Aminoacyl-tRNA synthetases, which help translate the genetic code into protein, also function in angiogenesis, fat metabolism, and more.

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