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tag stephen baylin culture genetics genomics microbiology

bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Composite image showing genes radiating from tumor cells
Jumping Genes’ Role in Cancer
Diana Kwon | Mar 1, 2023 | 8 min read
Transposons may be key players in how tumors develop and spread, but they also keep cancer at bay in some circumstances.
Fish in a big blue aquarium
Microbes Responsible for Stealing Aquarium Medicine
Amanda Heidt | Feb 1, 2022 | 6 min read
Researchers discover that bacteria break down medicinal compounds for their nitrogen, solving a mystery that has vexed aquatic veterinarians for years.
Biochemistry
The Scientist Staff | Nov 9, 1997 | 3 min read
Edited by: Paul Smaglik J.G. Herman, A. Merlo, L. Mao, R.G. Lapidus, J.J. Issa, N.E. Davidson, D. Sidransky, S.B. Baylin, "Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers," Cancer Research, 55:4525-30, 1995. (Cited in more than 145 publications through October 1997) Comments by James G. Herman and Stephen B. Baylin, Johns Hopkins University Oncology Center During the high-profile days of genome building and gene sequenc
Decoding DNA: New Twists and Turns
The Scientist Marketing Team | Feb 20, 2013 | 6 min read
The Scientist takes a bold look at what the future holds for DNA research, bringing together senior investigators and key leaders in the field of genetics and genomics in this 3-part webinar series.
Dethroning E. coli?
Alison F. Takemura | Jun 23, 2016 | 1 min read
Some scientists hope to replace microbiology’s workhorse bacterium with fast-growing Vibrio natriegens.
Updated Sept 1
coronavirus pandemic news articles covid-19 sars-cov-2 virology research science
Follow the Coronavirus Outbreak
The Scientist | Feb 20, 2020 | 10+ min read
Saliva tests screen staff and students at University of Illinois; Study ranks species most susceptible to SARS-CoV-2 infection; COVID-19 clinical trials test drugs that inhibit kinin system
Making Things Grow: Insect Cells, Stem Cells, and Primary Cell Lines All Pose Challenges for Cell Culturists
Laura Defrancesco | Jun 21, 1998 | 5 min read
Date: June 22, 1998 Insect Cell Culture Media, Suppliers of Primary Cell Culture Media Advantages for Protein Expression Studies Since the mid-1950s cultures of insects--cockroaches, fruit flies, and leafhoppers, to name a few--have been the object of quiet study by physiologists and cell biologists. But along came genetic engineering and suddenly insect cultures have been put in the spotlight since they provide advantages over both bacterial and mammalian systems for recombinant protein prod
Bacteria Harbor Geometric “Organelles”
Amber Dance | Dec 1, 2018 | 10+ min read
Microbes, traditionally thought to lack organelles, get a metabolic boost from geometric compartments that act as cauldrons for chemical reactions. Bioengineers are eager to harness the compartments for their own purposes.
Monitoring Mutations with Microfluidics
Ruth Williams | Mar 15, 2018 | 3 min read
A device dubbed the “mother machine” enables real-time observation of mutagenesis in single bacterial cells.  

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