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tag cell based assays immunology microbiology

Bugs as Drugs to Boost Cancer Therapy
Danielle Gerhard, PhD | Jan 18, 2024 | 7 min read
Bioengineered bacteria sneak past solid tumor defenses to guide CAR T cells’ attacks.
A needle drawing up fluid from an unlabeled vial.
Cancer Vaccination as a Promising New Treatment Against Tumors
Shelby Bradford, PhD | Mar 15, 2024 | 10+ min read
Vaccination has beaten back infections for more than a century. Now, it may be the next big step in battling cancer.
TAg
Jeffrey Perkel | Apr 29, 2001 | 2 min read
Antigen-specific T lymphocytes must be quantified in order to gauge the quality of an immune response. Typically this is accomplished using cytotoxicity assays or limiting dilution analysis (LDA), but these techniques are lengthy and provide indirect quantitation. Also, LDA cannot count nonproliferative cells. In 1996, Stanford University's Mark Davis developed an alternative strategy that overcomes these problems.1 Davis generated phycoerythrin-conjugated tetramers of human lymphocyte antigen (
Top 7 in Immunology
Edyta Zielinska | Aug 2, 2011 | 3 min read
A snapshot of the most highly ranked articles in microbiology and related areas, from Faculty of 1000
Bio-Plex™ Pro Human SARS-CoV-2 Variant Neutralization Antibody Assays
Bio-Rad Introduces Bio-Plex Pro Human SARS-CoV-2 Variant Neutralization Antibody Assays to Quickly Measure Neutralizing Antibodies Against SARS-CoV-2 Virus
Bio-Rad Laboratories | Dec 23, 2021 | 2 min read
Bio-Rad Laboratories, Inc. (NYSE: BIO and BIOb), a global leader of life science research and clinical diagnostic products, announced the launch of the Bio-Plex™ Pro Human SARS-CoV-2 Variant Neutralization Antibody Assays, for research use only (RUO).
A New Place in Human Immunology
Cynthia Fox | Jun 11, 2000 | 9 min read
Four class 1 molecules are constructed around a fragment of protein from a virus to make a tetramer Which of the following comments are immunologists making about the tetramer assay these days? A) "It's changed our life." B) "It's just an assay." If you answered "both," you're up on your immunology. The tetramer is just an assay, but it's been making immunologists giddy in the last few years. Peter Doherty of St. Jude Children's Research Hospital made the first statement (wh
3D illustration of a tapeworm infestation in a human intestine
Return of the Worms
Catherine Offord | Dec 1, 2021 | 10+ min read
Immunologists and parasitologists are working to revive the idea that helminths, and more specifically the molecules they secrete, could help treat allergies and autoimmune disease.
A white lab mouse peers over the wall of a sprawling maze
Bacterial Metabolite May Regulate Cognition in Mice
Sophie Fessl, PhD | Jun 3, 2022 | 3 min read
Microbes in the gut influence the death of support cells in the brain by producing isoamylamine, a study suggests.
Assays Galore
Lanette Fee | Sep 21, 2003 | 9 min read
Courtesy of BD Biosciences Pharmingen  COLOR CODING: Multiplexed bead-based assays, like BD Biosciences' Cytometric Bead Array (shown), test for multiple analytes in a single vial. The key is in the colors: one hue indicates the bead ID, and the intensity of the second, how much protein has been captured. In today's fast-paced research environment, technologies for speedy, cost-efficient analyses reign supreme. As part of this general trend, techniques for multiplexing, that is, simultan
Assays by the Score
Deborah Fitzgerald | May 27, 2001 | 9 min read
Click to view the PDF file: Bead-based Fluorescent Multiplex Protein Analysis Systems Courtesy of LINCO ResearchLabMAP-based systems use internally dyed fluorescent microspheres to analyze as many as 100 different analytes concurrently. Today's competitive, high-paced research environment has stimulated the development of a host of approaches for rapid, cost-efficient analyses of large numbers of samples. In keeping with this trend, methods for simultaneously analyzing multiple species in a g

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