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Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Monoclonal Antibodies Find Utility In Cell Biology
Ricki Lewis | Dec 11, 1994 | 10+ min read
But, just as antibodies are finding increasing utility in cell biology, a new Food and Drug Administration classification for those products with clinical utility may affect researchers' access to the important technology (see accompanying story). Monoclonal History MAbs were born in 1975, when Georges Kohler and Cesar Milstein at the Medical Research Council Laboratories in Cambridge, England, fused two types of cells to form a hy
Monoclonal Antibodies Find Utility In Cell Biology
Ricki Lewis | Dec 11, 1994 | 10+ min read
But, just as antibodies are finding increasing utility in cell biology, a new Food and Drug Administration classification for those products with clinical utility may affect researchers' access to the important technology (see accompanying story). Monoclonal History MAbs were born in 1975, when Georges Kohler and Cesar Milstein at the Medical Research Council Laboratories in Cambridge, England, fused two types of cells to form a hy
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The Booming Call of De-extinction
W. S. Roberts | Oct 19, 2020 | 6 min read
Scientists seek to combine genome editing with a technique used in chicken breeding to try to bring back lost birds.
colonies of mold growing on a Petri dish
Fungi Squeezed Through Microchannels Offer Clues to Cell Growth
Catherine Offord | Jun 1, 2021 | 3 min read
A study finds that fast-growing species are stymied by narrow gaps, while slower-growing species can pass through and continue extending.
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Our Favorite Genetics Stories of 2021
Christie Wilcox, PhD | Dec 23, 2021 | 4 min read
Studies The Scientist covered this year illustrate the expanding importance of genetic and genomic research in all aspects of life science, from ecology to medicine.
Surpassing the Law of Averages
Jeffrey M. Perkel | Sep 1, 2009 | 7 min read
By Jeffrey M. Perkel Surpassing the Law of Averages How to expose the behaviors of genes, RNA, proteins, and metabolites in single cells. By necessity or convenience, almost everything we know about biochemistry and molecular biology derives from bulk behavior: From gene regulation to Michaelis-Menten kinetics, we understand biology in terms of what the “average” cell in a population does. But, as Jonathan Weissman of the University of Califo
Contributors
The Scientist | Sep 1, 2020 | 4 min read
Meet some of the people featured in the September 2020 issue of The Scientist.
Woods Hole Lab Faces Uncertain Future
Elizabeth Pennisi | Aug 7, 1988 | 10 min read
Celebrating its centennial, the Marine Biological Laboratory adapts to a new era in which money talks as loudly as science WOODS HOLE, MASS.—When Harlyn 0. Halvorson, the new director of the Marine Biological Laboratory in Woods Hole, blows out the candles for his institution’s 100th birthday this summer, no one will have to ask what he wished for. The laboratory needs more money, more room, and more molecular biology if it is to remain in the forefront of scientific research durin
Conceptual image showing molecules making up a brain shape
The Noncoding Regulators of the Brain
Christie Wilcox, PhD | Sep 12, 2022 | 10+ min read
Noncoding RNAs are proving to be critical players in the evolution of brain anatomy and cognitive complexity.

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