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tag c difficile immunology genetics genomics microbiology

bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Bugs as Drugs to Boost Cancer Therapy
Danielle Gerhard, PhD | Jan 18, 2024 | 7 min read
Bioengineered bacteria sneak past solid tumor defenses to guide CAR T cells’ attacks.
Setting Standards for Stool
Aparna Nathan, PhD | Jan 19, 2024 | 10+ min read
Microbiome studies have yielded hundreds of ideas for ways to detect and influence human health, but the field struggles with reproducibility challenges that hamper bringing these goals to fruition. Identical tubes of fecal matter should help.
Bacterial Cocktail Treats Infection
Edyta Zielinska | Oct 28, 2012 | 1 min read
Mice fed a mix of six strains of bacteria were able to fight a C. difficile infection that causes deadly diarrhea and is resistant to most types of treatment.
The Scientist Staff | Mar 28, 2024
Top 7 in Immunology
Edyta Zielinska | Aug 2, 2011 | 3 min read
A snapshot of the most highly ranked articles in microbiology and related areas, from Faculty of 1000
Biosensors for Colorectal Cancer
Hannah Thomasy, PhD | Nov 1, 2023 | 4 min read
Engineered bacteria sound the alarm on a common oncogenic mutation.
Genetics
The Scientist Staff | Apr 26, 1998 | 3 min read
DUAL ROLE: Ronald DePinho, a professor at the Albert Einstein College of Medicine, helped to both identify INK4a as a tumor suppressor and to demonstrate its involvement in the Rb and p53 pathways. M. Serrano, H. Lee, L. Chin, C. Cordon-Cardo, D. Beach, R.A. DePinho, "Role of the INK4a locus in tumor suppression and cell mortality," Cell, 85:27-37, 1996. (Cited in more than 134 publications to date) Comments by Ronald A. DePinho, Department of Microbiology and Immunology, Albert Einstein C
A section of a mouse distal colon showing luminal contents with bacteria in magenta, the mucus lining (green) and the epithelial cell barrier of the gut (blue, right).
Mapping the Neighborhoods of the Gut Microbiome
Abby Olena, PhD | Jul 1, 2022 | 7 min read
Researchers are going beyond fecal samples to understand how the patterns of commensal microbes in the gastrointestinal tract influence development and health.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.

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