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tag double helix genetics genomics evolution

Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Illustration of DNA
Can “Gene Writing” Deliver What Gene Editing Can’t?
Dan Robitzski | Dec 12, 2022 | 10+ min read
A biotech startup called Tessera Therapeutics has made a splash with its claims about the trademarked technology. Is the excitement justified?
multicolor DNA sequencing gel
Genetic Mutations Can Be Benign or Cancerous—a New Method to Differentiate Between Them Could Lead to Better Treatments
Ryan Layer, The Conversation | May 27, 2022 | 5 min read
Tumors contain thousands of genetic changes, but only a few are actually cancer-causing. A quicker way to identify these driver mutations could lead to more targeted cancer treatments.
Judging DNA
Brendan Maher | Jan 12, 2003 | 5 min read
Courtesy of National Library of Medicine Marshall W. Nirenberg, laboratory chief of biochemical genetics at the National Institutes of Health's National Heart, Lung, and Blood Institute, received a Nobel Prize in 1968 for helping to interpret the genetic code and its function in protein synthesis. Q: How did the discovery of the double-helix structure relate to the cracking of the genetic code? A: George Gamow, the physicist, told me he went down his driveway to pick up the mail one day and
Decoding Human Accelerated Regions
Katherine S. Pollard | Aug 1, 2016 | 10 min read
Do the portions of our genomes that set us apart from other animals hold the secret to human evolution?
Nonradioactive Probes Protect Scientists And Environment
Holly Ahern | Apr 29, 1990 | 5 min read
For many years, geneticists determined the genetic makeup of organisms by examining the physical characteristics of their offspring. But with the discovery of the structure of the DNA double helix, first published by James D. Watson and Francis H.C. Crick in 1953 (Nature, 171:964-7), the science of genetics was forever changed. Scientists soon developed techniques to study the genetic message found in all living cells at the molecular level. One of most important of these methods was the use of
Genome Economy
Ricki Lewis | Jun 10, 2001 | 10 min read
The Human Genome Project's discovery1 that the human body runs on an instruction manual of a mere 35,000 or so genes--compared to the worm's 19,000, the fruit fly's 13,000, and the tiny mustard relative Arabidopsis thaliana's 25,000--placed humanity on an even playing field with these other, supposedly simpler, organisms. It was a humbling experience, but humility quickly gave way to awe with the realization that the human genome might encode 100,000 to 200,000 proteins. Scientists base this num
Science Museums Exhibit Renewed Vigor
Christine Bahls | Mar 28, 2004 | 10+ min read
Erica P. JohnsonApreschool girl with black braids presses a finger to a disk that twists a brightly lit DNA model, transforming its ladder shape into a double helix. Her head bops from side to side in wonder as the towering DNA coils and straightens. When a bigger boy claims her place, the girl joins meandering moms and dads with their charges as they twist knobs, open flaps, and simply stare at flashing helixes and orange information boards: all a part of the museum exhibit called "Genome: The
Jumping Genes a Cause of Cancer?
Ruth Williams | Jun 28, 2012 | 3 min read
Genome sequence analysis confirms mobile genetic elements are a mutagenic mechanism in a variety of cancers.
THE STATE OF LIFE SCIENCE
Dennis Meredith | Apr 1, 2007 | 8 min read
By Dennis MeredithTHE STATE OF LIFE SCIENCENorth Carolina combines academic, industrial, government, and private resources to drive research, development, and manufacturing A half century ago, the world was only beginning to grasp the stunning implications of Watson's and Crick's double-helix DNA structure. Amidst those earliest glimmerings of the genetic revolution, North Carolina was already laying the foundation for its 21st-century success in biotechnology. In 1959, however, the evidence o

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