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tag sleep wake cycle evolution microbiology genetics genomics

Who Sleeps?
The Scientist and Jerome Siegel | Mar 1, 2016 | 10+ min read
Once believed to be unique to birds and mammals, sleep is found across the metazoan kingdom. Some animals, it seems, can’t live without it, though no one knows exactly why.
A Nile rat sitting atop fruits
Genome Spotlight: Nile Rat (Avicanthis niloticus)
Christie Wilcox, PhD | Nov 23, 2022 | 4 min read
A reference sequence for this emerging model organism will facilitate research on type 2 diabetes and the health effects of circadian rhythm disruption.
An illustration of green bacteria floating above neutral-colored intestinal villi
The Inside Guide: The Gut Microbiome’s Role in Host Evolution
Catherine Offord | Jul 1, 2021 | 10+ min read
Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
bacteria inside a biofilm
How Bacterial Communities Divvy up Duties
Holly Barker, PhD | Jun 1, 2023 | 10+ min read
Biofilms are home to millions of microbes, but disrupting their interactions could produce more effective antibiotics.
Monitoring Mutations with Microfluidics
Ruth Williams | Mar 15, 2018 | 3 min read
A device dubbed the “mother machine” enables real-time observation of mutagenesis in single bacterial cells.  
Week in Review: January 20–24
Tracy Vence | Jan 23, 2014 | 3 min read
Mistimed sleep disrupts human transcriptome; canine tumor genome; de novo Drosophila genes; UVA light lowers blood pressure; aquatic microfauna fight frog-killing fungus
Circadian Clock Genes Help a Crop Pest Adapt to Climate Change
Emily Makowski | Jan 13, 2020 | 3 min read
As global temperatures rise and winters shorten, caterpillars of the corn borer moth are emerging earlier in parts of the US thanks to changes in two genes, researchers find.
Keeping Time with Drosophila
Laura Bonetta | Feb 3, 2002 | 10 min read
Circadian clocks—the biological timekeepers that operate on a daily cycle—keep virtually every living creature in tune with its environment. These internal clocks regulate a wide range of fundamental biological processes, including movement, smell, sleep, mating, and feeding. A true circadian clock is endogenous; that is, it keeps time even in the absence of external cues. The clock can, however, be reset, or entrained, by daylight, allowing the synchronization of circadian rhythms t
Frontlines
Harvey Black | Sep 1, 2002 | 6 min read
Frontlines Photo: University of Texas Health Science Center at Houston Opportunities in Allison's wake Since Hurricane Allison struck last June, researchers at the University of Texas Health Science Center, Houston, have been rebuilding and improving their facilities. "We said, 'Let's not just build back what we had, let's aim to do it better,'" says George Stencel, interim vice president for research. He estimates the project's cost in the "several hundred million dollar" range (H. Black,

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