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image: Scientists Stretch Neurons to Image Fine Structures

Scientists Stretch Neurons to Image Fine Structures

By | April 18, 2017

A double-expansion technique embeds brain tissue in the absorbent material of diapers to stretch out cells for easier visualization.

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By converting glial cells into dopaminergic neurons, scientists were able to partially rescue motor behavior in mice.

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image: Barcoding the Connectome

Barcoding the Connectome

By | November 11, 2016

Watch how researchers use RNA to track where neurons' axons end in the mouse brain.

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image: Neural Connectome Method Uses mRNA Barcodes

Neural Connectome Method Uses mRNA Barcodes

By | November 1, 2016

Researchers swap microscopy for RNA sequencing to track neural paths in the mouse brain.  

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image: Genetic Tags Illuminate Where Neurons Extend

Genetic Tags Illuminate Where Neurons Extend

By | November 1, 2016

Barcodes of mRNA travel to the cells' axon terminals, offering a sequencing-based approach to neural mapping.

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image: Two-Photon Microscopy’s Historic Influence on Neuroscience

Two-Photon Microscopy’s Historic Influence on Neuroscience

By | November 1, 2016

In the 1990s, the development of this gentler and more precise microscopy method improved scientists’ ability to probe neurons’ activity and anatomy.

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image: Nascent Neurons Journey Through Newborn Brain

Nascent Neurons Journey Through Newborn Brain

By | October 6, 2016

Young cells make their way to the frontal lobe to create new circuits in the brains of infants, researchers report. 

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image: Specialized Neurons Encode Social Learning in Humans

Specialized Neurons Encode Social Learning in Humans

By | September 6, 2016

Activity in the anterior cingulate cortex corresponds with observing the behavior of others when their actions, or the subsequent outcomes, don’t match one’s expectation.

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Researchers use the CRISPR/Cas system to express three transcription-factor genes, changing the identities of mouse cells.

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image: Single-Cell RNA Sequencing Reveals Neuronal Diversity

Single-Cell RNA Sequencing Reveals Neuronal Diversity

By | June 23, 2016

Using a new approach to analyze the transcriptomes of thousands of individual cell nuclei in postmortem brains, researchers identify multiple neuronal subtypes.

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