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tag gene drive evolution developmental biology disease medicine

Infusion of Artificial Intelligence in Biology
Meenakshi Prabhune, PhD | Feb 23, 2024 | 10 min read
With deep learning methods revolutionizing life sciences, researchers bet on de novo proteins and cell mapping models to deliver customized precision medicines.
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
A three-dimensional rendered image of neuron cell network on black background.
Assembloids Unlock the Roles of Key Neurodevelopment Disease Genes
Aparna Nathan, PhD | Sep 27, 2023 | 3 min read
Brain-like tissue grown in a dish mimics critical periods for development and reveals how it can go wrong.
First Successful Gene Drive in Mammals
Abby Olena, PhD | Jan 23, 2019 | 4 min read
Researchers use a CRISPR-Cas9 strategy to expand a desired trait from 50 percent of mouse pups to about 72 percent.
Illustration showing the upper part of a human body connected to a DNA helix
Unraveling the Mystery of Zombie Genes
Iris Kulbatski, PhD | Oct 31, 2023 | 6 min read
Digging into how and why some genes are resurrected after death sounds morbid, but it has practical applications. 
A bat flying in a dark cave
Turning on the Bat Signal
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
PCR tubes placed into the 96-well loading chamber of a PCR thermocycler instrument.
Directing Superior Reagents for Better PCR Results
The Scientist and MilliporeSigma | Oct 2, 2023 | 3 min read
Directed evolution approaches are creating new reagents to help a tried-and-true technique reach new heights.
Exploring the Past, Present, and Future of Brain Organoids 
Niki Spahich, PhD | Feb 18, 2024 | 5 min read
Paola Arlotta seeks to understand the complex symphony of brain development in vitro by using organoid models.
Genes that Escape Silencing on the Second X Chromosome May Drive Disease
Amber Dance | Mar 1, 2020 | 10+ min read
When X-linked genes evade silencing on the “inactive” chromosome in XX cells, some protect women from diseases such as cancer, but others seem to promote conditions such as autoimmunity.

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