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tag oxitec cell molecular biology disease medicine immunology

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
3D illustration of damaged myelin sheath seen in demyelinating diseases such as multiple sclerosis.
Tracking Down Innate Immune Cells in Multiple Sclerosis
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 5 min read
A novel PET tracer targeting a receptor in myeloid cells can help monitor disease progression in a mouse model of multiple sclerosis.
A bat flying in a dark cave
Turning on the Bat Signal
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
Macrophages on the Fast Track to Tumor Defense
Laura Tran, PhD | Feb 22, 2024 | 3 min read
In a race to the tumor, a macrophage’s phenotype can give it a leg up on the competition.
Artist&rsquo;s rendition of multiple <em>Neisseria gonorrhoeae</em>, the bacteria that causes gonorrhea, depicted as two spheres stuck together, each covered in tendrils.
Gonorrhea-Blocking Mutation Also Protects Against Alzheimer’s: Study
Holly Barker, PhD | Aug 5, 2022 | 4 min read
Research traces the evolution of a gene variant that reduces the risk of Alzheimer’s disease, finding that it originally evolved in response to infectious bacteria.
Immunology
The Scientist Staff | Apr 2, 1995 | 2 min read
Edited by: Neeraja D. Sankaran R.M. Chicz, R.G. Urban, J.C. Gorga, D.A.A. Vignali, W.S. Lane, J.L. Strominger, "Specificity and promiscuity among naturally processed peptides bound to HLA-Dr alleles," Journal of Experimental Medicine, 178:27-47, 1993. (Cited in 107 publications through January 1995) Comments by Roman M. Chicz,department of molecular and cellular biology, Harvard University One of the most important findings in this article, according to its authors, was the observation of pr
A person lying on a bed checks the reading on a digital thermometer. A table with a bowl of oranges and various medications is in the background.
How Mild Is Omicron Really?
Dan Robitzski | Jan 14, 2022 | 9 min read
Early reports that Omicron causes less-severe disease than Delta seem to be borne out, but it’s not yet clear to what extent that’s due to the variant itself versus the populations it’s infecting.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Journal club logo on purple background
The Scientist's Journal Club: Transcriptomics
The Scientist | Sep 20, 2023 | 2 min read
Scientists discuss their latest findings on immune cell dynamics, neurodegenerative disease risk factors, and rare cell types obtained from bulk and single cell RNA sequencing experiments.
Immunology
The Scientist Staff | Nov 22, 1998 | 4 min read
K.C. Garcia, M. Degano, R.L. Stanfield, A. Brunmark, M.R. Jackson, P.A. Peterson, L. Teyton, I.A. Wilson, "An alpha-ß T cell receptor structure at 2.5Å and its orientation in the TCR-MHC complex," Science, 274:209-19, 1996. (Cited in more than 240 papers since publication) Comments by Ian A. Wilson, professor of molecular biology at The Scripps Research Institute in La Jolla, Calif. D.N. Garboczi, P. Ghosh, U. Utz, Q.R. Fan, W.E. Biddison, D.C. Wiley, "Structure of the complex bet

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