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Harvesting lab-raised zebrafish based on their size led to differences in the activity of more than 4,000 genes, as well as changes in allele frequencies of those genes, in the fish that remained.

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image: More Details on How Pesticides Harm Bees

More Details on How Pesticides Harm Bees

By | May 3, 2017

Scientists report that thiamethoxam exposure impairs bumblebees’ reproduction and honey bees’ ability to fly.

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image: Rare T Cells Fight Cancer

Rare T Cells Fight Cancer

By | May 1, 2017

A new approach to immunotherapy finds that the immune-cell clonotypes that come to the rescue start out at very low frequencies.

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From fish harvests to cottonwood forests, organisms display evidence that species change can occur on timescales that can influence ecological processes.

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Guppies transplanted between different communities in Trinidadian streams evolved in response to changes in predation threat in just a few generations.

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image: Migratory Eels Use Magnetoreception

Migratory Eels Use Magnetoreception

By | April 14, 2017

In laboratory experiments that simulated oceanic conditions, the fish responded to magnetic fields, a sensory input that may aid migration.

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image: Contributors

Contributors

By | April 1, 2017

Meet some of the people featured in the April 2017 issue of The Scientist.

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image: Gel Scaffolds for Delivery of Immunotherapies

Gel Scaffolds for Delivery of Immunotherapies

By | April 1, 2017

Using biocompatible polymers to carry cancer immune therapies directly to the tumor

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image: Making CAR T-Cell Therapy Safer

Making CAR T-Cell Therapy Safer

By | April 1, 2017

Following a spate of patient deaths in clinical trials testing modified T cells for the treatment of cancer, researchers work to reduce the treatment’s toxicity without sacrificing efficacy.

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Measuring PD-L1 levels was a great start. Now we need to quantify more protein biomarkers, assess the tumor mutational landscape, and examine immune cell signatures, too.

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