mitochondria, cell & molecular biology, disease & medicine

A handful of clinical trials are underway to find out whether drugs that target senescent cells can slow the ravages of old age.

The accumulation of zombie-like cells seems to accelerate aging and promote aging-related disease. Researchers are trying to figure out how.

New evidence points to a waste-clearing problem in patients’ cells, rather than the accumulation of protein tangles, as the root cause of the neurodegenerative disease.

Damage to the lysosome, the organelle that removes excess proteins, lipids, and other materials, might be at the root of the disease.

Even if people exercise, hydrogen peroxide and other reactive molecules continue to accumulate in the tissues.

Among 11 infants treated to date, most survived and their heart function improved.