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image: Deep Pocket Exploration

Deep Pocket Exploration

By | February 1, 2017

A modification to traditional docking software enables the examination of a ligand’s passage into its receptor.

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image: Infographic: Modeling Molecules’ Receptor Binding

Infographic: Modeling Molecules’ Receptor Binding

By | February 1, 2017

A software upgrade follows ligands step-wise into their binding sites on receptors.

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image: Unique Antibodies Open Path Toward New HIV Vaccines

Unique Antibodies Open Path Toward New HIV Vaccines

By | January 27, 2017

A family of broadly neutralizing antibodies from a chronically infected donor provides a schematic for designing vaccines and treatments that target multiple strains of the virus.

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A test tube-based genome-labeling technique has been brought under the microscope.

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image: Mouse Immunology Paper Retracted

Mouse Immunology Paper Retracted

By | December 16, 2016

A finding of misconduct spurs the retraction of a Science paper claiming to have identified a protein in mice that boosted immunity to both viruses and cancer.

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image: Top Technical Advances 2016

Top Technical Advances 2016

By | December 15, 2016

The year’s most impressive achievements include methods to watch translation in cells, trace cell fates, avoid mitochondrial mutations, edit DNA, and build antibiotics from scratch.

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image: Naive T Cells Find Homes in Lymphoid Tissue

Naive T Cells Find Homes in Lymphoid Tissue

By | December 2, 2016

The human lymph nodes and spleen maintain unique, compartmentalized sets of naive T cells well into old age.

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image: Synthetic Sensors

Synthetic Sensors

By | December 1, 2016

Engineered circuits detect endogenous transcription factors to drive cellular outputs.

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image: Infographic: How to Build a Synthetic Sensor

Infographic: How to Build a Synthetic Sensor

By | December 1, 2016

Scientists designed a genetic sensor-and-readout system, based on detecting a transcription factor, that performs a custom cellular activity.

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image: Low Social Status May Weaken Immune System in Monkeys

Low Social Status May Weaken Immune System in Monkeys

By | November 29, 2016

Life at the bottom of the pecking order ramps up inflammation, according to new research, an effect that appears to be reversible.

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